Protein Info for ABIE41_RS19935 in Bosea sp. OAE506

Annotation: GTPase Era

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 TIGR00231: small GTP-binding protein domain" amino acids 16 to 173 (158 residues), 79.1 bits, see alignment E=3.3e-26 TIGR00436: GTP-binding protein Era" amino acids 16 to 286 (271 residues), 256.6 bits, see alignment E=2.6e-80 PF01926: MMR_HSR1" amino acids 18 to 132 (115 residues), 81.1 bits, see alignment E=2.7e-26 PF10662: PduV-EutP" amino acids 18 to 176 (159 residues), 31.8 bits, see alignment E=4.7e-11 PF02421: FeoB_N" amino acids 18 to 141 (124 residues), 49 bits, see alignment E=2e-16 PF02492: cobW" amino acids 57 to 145 (89 residues), 26.4 bits, see alignment E=2e-09 PF07650: KH_2" amino acids 215 to 291 (77 residues), 59.2 bits, see alignment E=1.1e-19

Best Hits

Swiss-Prot: 67% identical to ERA_RHIME: GTPase Era (era) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03595, GTP-binding protein Era (inferred from 74% identity to mno:Mnod_7362)

Predicted SEED Role

"GTP-binding protein Era" in subsystem Bacterial Cell Division or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (308 amino acids)

>ABIE41_RS19935 GTPase Era (Bosea sp. OAE506)
MADETGGAPTGPTRAGFVALIGAPNAGKSTLLNQLVGAKVSIVSRKVQTTRTQVRGIAMS
GAAQIIFVDTPGIFQPKRRLDRAMVTSAWGGATDADLIGVLIDVERFDNEENTRLLEKLA
ELKQPKFLILNKIDIIAKDKLLEITAKVNALGSFETTFMIAALTGYGVKDILAWLETRLP
LGPWLYPEDQISDAPLRFLAAEITREKIFERLHDELPYRSTVETEQWQQRPDGSVRIEQT
IYVEREGQRKIVLGEGGQTIKAIGQKARVEIAEAAEATVHLFLFVKVRENWSDDPARYRE
MGLEFPKG