Protein Info for ABIE41_RS18335 in Bosea sp. OAE506

Annotation: polysaccharide deacetylase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: None (inferred from 68% identity to rde:RD1_2422)

Predicted SEED Role

"Uricase (urate oxidase) (EC 1.7.3.3)" (EC 1.7.3.3)

MetaCyc Pathways

ureide biosynthesis (6/7 steps found)
superpathway of purines degradation in plants (13/18 steps found)
urate conversion to allantoin I (2/3 steps found)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.7.3.3

Use Curated BLAST to search for 1.7.3.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (302 amino acids)

>ABIE41_RS18335 polysaccharide deacetylase family protein (Bosea sp. OAE506)
MTHRDLEGYAGAWPDFTWPNGRRLAISVVINFEEGAELQVGDGDARSESMGEVMSIVPAG
KRDQGQEQIFGYGTRAGLWRMLDALDDSAIRSTIFFCGRAVERSPALAKAVVARGHEPAV
HGWRWRPHADYETAEAEAADIDACVATITAATGVTPVGFFCRGGESPWTRELLAQRGFLY
TSNGFDDDLPYWDRAPGRPPLLVVPYALDSNDMKFFHPNGFVRSREMVEYVTDALDVLEA
EAARGLPRLLNLGFHLRIVGRPARFAAFRDIMCLLAARRDRLWIAGRAEIARAFIAAVPE
SP