Protein Info for ABIE41_RS18235 in Bosea sp. OAE506

Annotation: ATP-dependent Clp protease ATP-binding subunit ClpA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 TIGR02639: ATP-dependent Clp protease ATP-binding subunit ClpA" amino acids 5 to 752 (748 residues), 1135.7 bits, see alignment E=0 PF02861: Clp_N" amino acids 15 to 64 (50 residues), 46.3 bits, see alignment 3e-15 PF00004: AAA" amino acids 230 to 362 (133 residues), 51.7 bits, see alignment E=9.3e-17 amino acids 511 to 626 (116 residues), 45.9 bits, see alignment E=6.1e-15 PF17871: AAA_lid_9" amino acids 370 to 472 (103 residues), 95.9 bits, see alignment E=9.3e-31 PF07724: AAA_2" amino acids 505 to 665 (161 residues), 196.8 bits, see alignment E=2.1e-61 PF13401: AAA_22" amino acids 508 to 602 (95 residues), 28.5 bits, see alignment E=1.3e-09 PF00158: Sigma54_activat" amino acids 511 to 632 (122 residues), 25 bits, see alignment E=1e-08 PF07728: AAA_5" amino acids 511 to 627 (117 residues), 48 bits, see alignment E=1e-15 PF10431: ClpB_D2-small" amino acids 672 to 752 (81 residues), 92.6 bits, see alignment E=9.3e-30

Best Hits

KEGG orthology group: K03694, ATP-dependent Clp protease ATP-binding subunit ClpA (inferred from 82% identity to bid:Bind_1667)

Predicted SEED Role

"ATP-dependent Clp protease ATP-binding subunit ClpA" in subsystem Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (850 amino acids)

>ABIE41_RS18235 ATP-dependent Clp protease ATP-binding subunit ClpA (Bosea sp. OAE506)
MPSFSRSLEQALHRALALANERHHEYATLEHLLLALVDDQDAAAVMRACSVDLDTLRRSL
VDYIDAELANLVTDGRDDSKPTAGFQRVIQRAVIHVQSSGREEVTGANVLVAMFAERESH
AAYFLQEQDMTRYDAVNYISHGIAKRPGASEARPVRGVEEEPEQQRDSRAADPGNDADKD
KKKKESALDAYCVNLNRKARDGRIDPLIGREAEVQRTIQILCRRQKNNPLLVGDPGVGKT
AIAEGLALKITRGQVPEVLEDATVFSLDMGTLLAGTRYRGDFEERLKQVMKEIEAHPKAI
MFIDEIHTVIGAGATSGGAMDASNLLKPALASGSLRCIGSTTYKEYRQYFEKDRALVRRF
QKIDVSEPSIPDAVEILKGLKPYFEEFHKLRYTNDAIKAAVELSARYIHDRKLPDKAIDV
IDETGASQMLVAENKRKKTIGVKEIEAAIATMARIPAKTVSKDDAEVLRNLETTLKRTVY
GQEKAIEALSSSIKLARAGLRDGEKPIGCYLFAGPTGVGKTEVARQLATSLGVELIRFDM
SEYMERHTVSRLIGAPPGYVGFDQGGLLTDQIDQHPHSVLLLDEIEKAHPDLFNILLQVM
DHGKLTDNNGKQVDFRNVILIMTTNAGAADMARNAYGFTRQKREGDDTEAINKLFAPEFR
NRLDSVVSFGHLPKTVVARVVDKFVLQLEAQLADRNVTIELSDEAREWLVENGYDEAMGA
RPMARLIQQTIKTPLADEVLFGRLKNGGAVRVVVVQSETGIKVLGLEFPDGPVKPKPEKD
VAAAAEKRERKPRAKAAAAKPAPAAPRRSGPAGKAGKGDGGGKGDGGKGPEAPKAQRSVR
TVPKVPLTKA