Protein Info for ABIE41_RS16625 in Bosea sp. OAE506

Annotation: FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 469 signal peptide" amino acids 18 to 34 (17 residues), see Phobius details transmembrane" amino acids 384 to 396 (13 residues), see Phobius details PF01494: FAD_binding_3" amino acids 16 to 208 (193 residues), 39.7 bits, see alignment E=1.3e-13 PF00890: FAD_binding_2" amino acids 17 to 437 (421 residues), 184.2 bits, see alignment E=1.8e-57 PF07992: Pyr_redox_2" amino acids 17 to 202 (186 residues), 29.3 bits, see alignment E=2.2e-10 PF03486: HI0933_like" amino acids 17 to 47 (31 residues), 25.1 bits, see alignment (E = 2.6e-09) PF01266: DAO" amino acids 17 to 208 (192 residues), 51.9 bits, see alignment E=3e-17 PF12831: FAD_oxidored" amino acids 17 to 87 (71 residues), 28.3 bits, see alignment E=4e-10 PF13450: NAD_binding_8" amino acids 20 to 54 (35 residues), 28.9 bits, see alignment 3.9e-10

Best Hits

KEGG orthology group: K00244, fumarate reductase flavoprotein subunit [EC: 1.3.99.1] (inferred from 68% identity to azc:AZC_2105)

Predicted SEED Role

"Fumarate reductase flavoprotein subunit (EC 1.3.99.1)" in subsystem Succinate dehydrogenase (EC 1.3.99.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.1

Use Curated BLAST to search for 1.3.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (469 amino acids)

>ABIE41_RS16625 FAD-dependent oxidoreductase (Bosea sp. OAE506)
MNAVLPASGRSFEAQADVLIIGAGAAGLVAALAASEAGAEVVVLERDAVPSGSTALSAGL
IPAADTRFQRAAGIADSAELFAADIMAKAENEPDAAIVARLAAHVGGVLEWLADRHGLPF
DVVTNFSYPGHSARRMHGLPKRTGSELVDRLREAAEARDIPILTHCRVTTLFADEASCIV
GVAGTRPDGREETIGCKALVLACNGYGGHRDLVATYIPEMADALWFGHSGNEGDAVLWGE
ALGADLVDMSGHQGHGSVAQPHGILITWATIMEGGFQVNARGKRFSDESHGYSEQAATVL
AQPDGKAWTIFDGRIAGIARQFEDFRNAEAQGAILQAQDLSELAAMLGLPPDALAATAAE
VEALKQGDGADRFGRDFRGAAPLVAPFCAVAVTGALFHTQGGLRINPEARVLRPDGSAFA
NLFACGGAAVGVSGRRASGYLSGNGLLTAITLGDIAGRAAARLSSADPA