Protein Info for ABIE41_RS16615 in Bosea sp. OAE506

Annotation: hydantoinase/oxoprolinase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 PF05378: Hydant_A_N" amino acids 10 to 180 (171 residues), 150.4 bits, see alignment E=6.8e-48 PF01968: Hydantoinase_A" amino acids 202 to 490 (289 residues), 286.3 bits, see alignment E=3.8e-89 PF19278: Hydant_A_C" amino acids 520 to 677 (158 residues), 47.4 bits, see alignment E=2.4e-16

Best Hits

KEGG orthology group: K01473, N-methylhydantoinase A [EC: 3.5.2.14] (inferred from 75% identity to met:M446_1935)

Predicted SEED Role

"N-methylhydantoinase A (EC 3.5.2.14)" in subsystem Hydantoin metabolism (EC 3.5.2.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.14

Use Curated BLAST to search for 3.5.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (686 amino acids)

>ABIE41_RS16615 hydantoinase/oxoprolinase family protein (Bosea sp. OAE506)
MTTSSPRAIVGVDVGGTFTDLFWFDEAAKRFRTAKVPSQRGDEAKGFIAGLTSFGPVSEL
ASIVHGTTVGTNALLERKGAKVGIITTPGFRDALEMRRRDRRQTWGLWGDFVPVAARDCR
VEVPERTLADGTIRLAVDREAVREAARALHEKGCEALAIIFINAYANPQNERDALEAARA
VWPNENIACSSAILPEIREFERSSTTALNATLQPVVGSYLGRLEDALAADGFTGRFHIVQ
SNGGVMSTATARRLPVRTALSGPAAGVIAAAVIARAAGHPDIITGDLGGTSFDVSLIAGG
QAALAAQTTIDFGMVIRTPMIEITTIGAGGGSIARVDAGGLLEVGPESAGSRPGPVCYGQ
GNTRPTLTDANLVLGRIDGEKPLGTLQRLDVEAARAAIAREIAEPLGLDVMAAAEAIVKI
ANARMAGAIRLVSIERGHDPAKFMAMPFGGGGALHAGALIHEVGLKGALVPRFPGVTSAL
GCVIADIRHDGVQTVNLMLEGLDAAALDARMVEAGREAHRVVAEAGLSVERIDVIYELDM
HYLGQTHTVSVPLPVTLGEDGTGITGDLIREAFEAAYGAAFSRLLPGIPLRIVTLRTAAI
GRRPAFDLTALAPAAEASLELARRGTRQVYLDGAWRETAIWSRLDLPVSARVEGPAIFEQ
PDATVLLDPGLTAEVDALGNLVILRS