Protein Info for ABIE41_RS15610 in Bosea sp. OAE506

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 514 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 55 to 75 (21 residues), see Phobius details amino acids 87 to 105 (19 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 145 to 166 (22 residues), see Phobius details amino acids 173 to 196 (24 residues), see Phobius details amino acids 208 to 227 (20 residues), see Phobius details amino acids 235 to 253 (19 residues), see Phobius details amino acids 273 to 298 (26 residues), see Phobius details amino acids 311 to 331 (21 residues), see Phobius details amino acids 339 to 358 (20 residues), see Phobius details amino acids 364 to 390 (27 residues), see Phobius details amino acids 411 to 429 (19 residues), see Phobius details amino acids 479 to 504 (26 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 416 (387 residues), 161.5 bits, see alignment E=2.7e-51 PF00083: Sugar_tr" amino acids 52 to 129 (78 residues), 26.2 bits, see alignment E=3.9e-10

Best Hits

Swiss-Prot: 44% identical to LFRA_MYCS2: Multidrug efflux pump LfrA (lfrA) from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

KEGG orthology group: K08167, MFS transporter, DHA2 family, methyl viologen resistance protein SmvA (inferred from 64% identity to pol:Bpro_1369)

Predicted SEED Role

"possible transmembrane-transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (514 amino acids)

>ABIE41_RS15610 MFS transporter (Bosea sp. OAE506)
MKPAPDMTATAPKATRRDWLGLAVIALPCLLYSMDLTVLNLAIPQLSVDLKPSAAQLLWI
VDIYGFMVAGSLITMGTLGDKIGRRKLLLIGAAAFGLASILAAFSTSAEMLIATRALLGI
AGATLAPSTLSLIRNMFLDSKERSFAIGIWIASFSAGGAIGPLVGGLLLEHYWWGSVFLV
GVPVMILLLALGPILLPEFKDPEAGRVDLASAVLSLVAVLAVIYGIKHLAEHGGGWEAAV
AILAGLTVGGVFLRRQRRLADPFLDLRLFRNPVISAALAINVLGFLFLFGSFLFIGQYLQ
LVKDFSPLEAGLWSLPSALAFILGTPIAPVLAHRFRPAPIMAVGLTLAALGFALLSRVTV
DSPIAIVVVAGVIFSLGFTPVVALTTELVVGSAPPERAGSAAAISETSLEFGGAVGIAVL
GSIVTAVYRGQMALTQPAGLPPDTARNAAATLGGAVAEAARLPADLAASLLAAARAAFVA
GMQLSALVATVGLFVTALTALVLLRKATATAHPA