Protein Info for ABIE41_RS12915 in Bosea sp. OAE506

Annotation: TetR/AcrR family transcriptional regulator C-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 222 PF00440: TetR_N" amino acids 21 to 64 (44 residues), 25.1 bits, see alignment 1.2e-09 PF14246: TetR_C_7" amino acids 91 to 208 (118 residues), 61.6 bits, see alignment E=7.1e-21

Best Hits

KEGG orthology group: None (inferred from 73% identity to sno:Snov_0329)

Predicted SEED Role

"Transcriptional regulator, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (222 amino acids)

>ABIE41_RS12915 TetR/AcrR family transcriptional regulator C-terminal domain-containing protein (Bosea sp. OAE506)
MTTTPPMTETDEPTARQQAVLDAVLSLMVEEGDQLTMTAVARRASCSKETLYKWFGDRDG
LLAATVRWQAARVRAGRYDRPTLDIATLRDSLKGFAATWLTVISSPTSIALNRLAIGHAA
SRKSNLGGIVLANGRFAIGERLRPVLEAGREAGLLAFADSETAFRTFFGLVGRDVQIRLL
LGDTLTLSRNEIERDAARATDQFLTLYGGRVPSQGSDETTRS