Protein Info for ABIE41_RS12260 in Bosea sp. OAE506

Annotation: superoxide dismutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00081: Sod_Fe_N
  • amino acids 42 to 128 (87 residues), 73.8 bits, E=1.3e-24
• PF02777: Sod_Fe_C
  • amino acids 136 to 237 (102 residues), 129.1 bits, E=6.4e-42

Best Hits

Swiss-Prot: 53% identical to SODM1_LEPBY: Superoxide dismutase [Mn] 1 (sodA1) from Leptolyngbya boryana

KEGG orthology group: K04564, superoxide dismutase, Fe-Mn family [EC: 1.15.1.1] (inferred from 64% identity to rpc:RPC_0485)

MetaCyc: 45% identical to superoxide dismutase (Mn) (Escherichia coli K-12 substr. MG1655)
Superoxide dismutase. [EC: 1.15.1.1]

Predicted SEED Role

"Manganese superoxide dismutase (EC 1.15.1.1)" in subsystem Nitric oxide synthase or Oxidative stress (EC 1.15.1.1)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• superoxide radicals degradation (2/2 steps found)
• ethene biosynthesis III (microbes) (5/7 steps found)

Isozymes

Compare fitness of predicted isozymes for: 1.15.1.1

Use Curated BLAST to search for 1.15.1.1

Protein Sequence (248 amino acids)

>ABIE41_RS12260 superoxide dismutase (Bosea sp. OAE506)
MTTTYSVSRRSLLGVGAAALAMAAAPRVWAQAAAPAAPAGPFSLPKRAYEAAALEPHIDA
MTMDIHYSRHHAAFVTALNNAAKDHGVLASKPINELLGDIGALPEAVRVPIRNAGGGHAN
HSMFWEIMGPGAGGAPTGDVAAAITKDLGGFDKFKADFEAAGLRVFGSGWVFVTVDKAGK
LALLAKPNQDSPLMDKQMVLLGNDVWEHAYYLKYQNRRADYLKGWWNVVNWAKVNERYAA
AKAGKLAV