Protein Info for ABIE41_RS10550 in Bosea sp. OAE506

Annotation: cytochrome-c oxidase, cbb3-type subunit III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 transmembrane" amino acids 36 to 58 (23 residues), see Phobius details TIGR00782: cytochrome c oxidase, cbb3-type, subunit III" amino acids 10 to 294 (285 residues), 362 bits, see alignment E=1.1e-112 PF14715: FixP_N" amino acids 16 to 61 (46 residues), 85.7 bits, see alignment 2.1e-28 PF13442: Cytochrome_CBB3" amino acids 114 to 198 (85 residues), 46.2 bits, see alignment E=7.3e-16 amino acids 212 to 287 (76 residues), 45.2 bits, see alignment E=1.4e-15 PF00034: Cytochrom_C" amino acids 115 to 201 (87 residues), 45.3 bits, see alignment E=2.7e-15 amino acids 213 to 282 (70 residues), 31.1 bits, see alignment E=7.3e-11

Best Hits

Swiss-Prot: 64% identical to FIXP_BRASO: Cbb3-type cytochrome c oxidase subunit FixP (fixP) from Bradyrhizobium sp. (strain ORS 278)

KEGG orthology group: K00406, cb-type cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 64% identity to bbt:BBta_2794)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (294 amino acids)

>ABIE41_RS10550 cytochrome-c oxidase, cbb3-type subunit III (Bosea sp. OAE506)
MAQHQDHHEVDAHTGVSTTGHEWDGIRELNTPLPRWWLGIFYATIVWSVGYWVVYPAWPL
ITGATKGVIGYASRIEIAKDLALLQQHRATQSSGLAEASLEQIKADPSLFRIAMAQGKAA
FGDNCAACHGVGGGGSKGYPNLNDDDWLWGGTLAEIHQTLQNGVRVAGNADSRISQMPAF
GKDGVLKPAEIRAVANHVRELAGLPTEQGADLVKGRELFATNCAACHGDAGKGNKELGAP
NLSDAISLYGMDMASLTETITNSRAGVMPAWGQRLDPTTVKALTIYVHSLGGGQ