Protein Info for ABIE41_RS09600 in Bosea sp. OAE506

Annotation: phosphoglucosamine mutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02878: PGM_PMM_I
  • amino acids 3 to 134 (132 residues), 154.9 bits, E=2.1e-49
• TIGR01455: phosphoglucosamine mutase
  • amino acids 6 to 443 (438 residues), 633.1 bits, E=1.1e-194
• PF02879: PGM_PMM_II
  • amino acids 158 to 255 (98 residues), 64.9 bits, E=1.8e-21
• PF02880: PGM_PMM_III
  • amino acids 259 to 367 (109 residues), 127.5 bits, E=5.8e-41
• PF00408: PGM_PMM_IV
  • amino acids 375 to 442 (68 residues), 56.4 bits, E=5.1e-19

Best Hits

Swiss-Prot: 83% identical to GLMM_METNO: Phosphoglucosamine mutase (glmM) from Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060)

KEGG orthology group: K03431, phosphoglucosamine mutase [EC: 5.4.2.10] (inferred from 83% identity to mno:Mnod_4549)

MetaCyc: 52% identical to phosphoglucosamine mutase (Escherichia coli K-12 substr. MG1655)
Phosphoglucosamine mutase. [EC: 5.4.2.10]

Predicted SEED Role

"Phosphoglucosamine mutase (EC 5.4.2.10)" in subsystem Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 5.4.2.10)

MetaCyc Pathways

• O-antigen building blocks biosynthesis (E. coli) (11/11 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis I (5/5 steps found)
• dTDP-β-L-rhamnose biosynthesis (5/5 steps found)
• glycogen degradation I (7/8 steps found)
• colanic acid building blocks biosynthesis (9/11 steps found)
• glycogen degradation II (5/6 steps found)
• superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis (5/6 steps found)
• UDP-α-D-glucose biosynthesis (2/2 steps found)
• sucrose biosynthesis I (from photosynthesis) (7/9 steps found)
• sucrose degradation II (sucrose synthase) (4/5 steps found)
• sucrose biosynthesis II (6/8 steps found)
• glycogen biosynthesis I (from ADP-D-Glucose) (3/4 steps found)
• starch degradation V (3/4 steps found)
• sucrose degradation IV (sucrose phosphorylase) (3/4 steps found)
• GDP-α-D-glucose biosynthesis (2/3 steps found)
• trehalose degradation V (2/3 steps found)
• glucose and glucose-1-phosphate degradation (3/5 steps found)
• starch degradation III (2/4 steps found)
• chitin biosynthesis (5/9 steps found)
• D-galactose degradation I (Leloir pathway) (2/5 steps found)
• glucosylglycerol biosynthesis (2/5 steps found)
• superpathway of anaerobic sucrose degradation (12/19 steps found)
• glycogen biosynthesis III (from α-maltose 1-phosphate) (4/8 steps found)
• peptidoglycan recycling I (8/14 steps found)
• starch biosynthesis (5/10 steps found)
• CDP-6-deoxy-D-gulose biosynthesis (1/5 steps found)
• CMP-legionaminate biosynthesis I (2/10 steps found)
• superpathway of dTDP-glucose-derived O-antigen building blocks biosynthesis (6/19 steps found)
• superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis (13/33 steps found)
• streptomycin biosynthesis (2/18 steps found)
• superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis (6/24 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.10

Protein Sequence (447 amino acids)

>ABIE41_RS09600 phosphoglucosamine mutase (Bosea sp. OAE506)
MTRKYFGTDGIRGRANGVITPDLALKVGQATGLAFQRGSHRHRVVIGKDTRLSGYMIEYA
MVAGFTSVGMDVMLLGPMPTPAVAMLTRSMRADLGVMISASHNPYEDNGIKLFGPDGYKL
SDEVEAEISKLIDSDLAPRLSNAPALGRAKRIESAHARYIEFAKRTLPRNMSLEGMRIVI
DCANGAGYKVAPEALWELGAEVIAIGIEPDGFNINKDVGSTAPDALIAKVRELRADIGIA
LDGDADRVLIVDELGQVVDGDQLMAVIARTWQEDGRLTQPGVVATVMSNLGLERYLAGLG
LSLARTAVGDRYVLEHMRSQGFNLGGEQSGHIILSDFGTTGDGLVAALQLLAAVKRQDKP
VSEVCHAFEPLPQILKNVRYKQGQPLKEKPVVSAIEAARQMLGESGRLVIRPSGTEPVIR
VMAEGDDRDLVMRAVDDIVEAVTKAAA