Protein Info for ABIE41_RS08230 in Bosea sp. OAE506

Annotation: amino acid ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 243 PF00005: ABC_tran" amino acids 19 to 167 (149 residues), 130 bits, see alignment E=1.5e-41 PF00931: NB-ARC" amino acids 27 to 228 (202 residues), 28.6 bits, see alignment E=1.3e-10

Best Hits

Swiss-Prot: 51% identical to NOCP_AGRFC: Nopaline permease ATP-binding protein P (nocP) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K02028, polar amino acid transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 79% identity to atu:Atu1396)

MetaCyc: 53% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Glutamate transport ATP-binding protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.21

Use Curated BLAST to search for 3.6.3.21 or 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (243 amino acids)

>ABIE41_RS08230 amino acid ABC transporter ATP-binding protein (Bosea sp. OAE506)
MPAVLIDDVHKRFGDLEVLKGVSLNVESGQVVALIGRSGSGKSTLLRCINGLEAINSGRI
EVAGHVVDQDPKKLRELRKDVGIVFQSYNLFPHLTVGQNIMLSPRITQNVPQDKAAELAR
EVLAQVGLSEKFDSYPDNLSGGQQQRVAIARSLAMRPKVMLFDEVTSALDPELTGEVLLV
MEKLAKNGMTMLLVTHEMSFARNVASTTVFMHQGKIWESGPSQELFANPQTPELRNFVSA
GSK