Protein Info for ABIE41_RS07305 in Bosea sp. OAE506

Annotation: isocitrate lyase/phosphoenolpyruvate mutase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 279 PF13714: PEP_mutase" amino acids 10 to 249 (240 residues), 247.1 bits, see alignment E=1e-77

Best Hits

KEGG orthology group: None (inferred from 63% identity to met:M446_6009)

Predicted SEED Role

"Probable carboxyvinyl-carboxyphosphonate phosphorylmutase (EC 2.7.8.23)" (EC 2.7.8.23)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (279 amino acids)

>ABIE41_RS07305 isocitrate lyase/phosphoenolpyruvate mutase family protein (Bosea sp. OAE506)
MAYPPQVDAFRALHASGCFVMPNPWDLGSARWLRGQGFKALATTSAGFAFTQGRADQDVP
RDMMLAHIAEMVKAVPDLPVNADFENGYADTPDGVAANVKLCVATGAAGLSIEDATGRED
DPLYPFELAVERIRAARKAIDETGSGVVLTARAECFLTAHPQAQAESVRRLEAYREAGAD
VLYAPGVRSAEQIAAIVAAAGGKPVNVVVFADFGLTVADFEALGVRRLSTGAASARSAWA
GFVESTRQIVEGGSFAGFAGNAPSRRLDPFFRDDLKARS