Protein Info for ABIE41_RS05110 in Bosea sp. OAE506

Annotation: zinc metalloprotease HtpX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 307 signal peptide" amino acids 1 to 11 (11 residues), see Phobius details transmembrane" amino acids 12 to 42 (31 residues), see Phobius details amino acids 141 to 164 (24 residues), see Phobius details amino acids 172 to 193 (22 residues), see Phobius details PF01435: Peptidase_M48" amino acids 65 to 273 (209 residues), 132.7 bits, see alignment E=7.4e-43

Best Hits

Swiss-Prot: 66% identical to HTPX_RHIEC: Protease HtpX homolog (htpX) from Rhizobium etli (strain CFN 42 / ATCC 51251)

KEGG orthology group: K03799, heat shock protein HtpX [EC: 3.4.24.-] (inferred from 64% identity to sno:Snov_3790)

Predicted SEED Role

"Probable protease htpX homolog (EC 3.4.24.-)" (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (307 amino acids)

>ABIE41_RS05110 zinc metalloprotease HtpX (Bosea sp. OAE506)
MNYVRTGMLMAGLTALFGAVGYLLGGGGGMLMALGFAAVTNLFSYWNSDRLALAAHNAHE
VDERTAPELYGMVRDLAARANMPMPRVYLIEEDQPNAFATGRNPENAAVAATTGILRTLS
YEELAGVMAHELAHIKNHDTLTMTITATMAGAISSLVTFGMMFGSRENRPNMVVQILLSI
LAPMAAMVIQMAISRSREYEADKLGAEICGNPVWLADALAKIAGGVAHTPNETAEAKPAT
AHMFIINPLTAGGMDSLFSTHPDTGNRIAALMEQARAMGIGRSGGGFVGGAAQNHWSGSG
REPGPWG