Protein Info for ABIE41_RS04730 in Bosea sp. OAE506

Annotation: response regulator transcription factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 228 PF00072: Response_reg" amino acids 7 to 118 (112 residues), 94.7 bits, see alignment E=4e-31 PF00486: Trans_reg_C" amino acids 152 to 226 (75 residues), 67.7 bits, see alignment E=7.7e-23

Best Hits

Swiss-Prot: 37% identical to PMRA_PECPM: Transcriptional regulatory protein PmrA (pmrA) from Pectobacterium parmentieri

KEGG orthology group: None (inferred from 72% identity to met:M446_1399)

Predicted SEED Role

"DNA-binding response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (228 amino acids)

>ABIE41_RS04730 response regulator transcription factor (Bosea sp. OAE506)
MPAVHHILLVDDDQTLRDALAEQLALYDEFKLSTAGTATAAVKAVQAERIDLAIMDVGLP
DMDGREAVKLMRKNGFKSPVIMLTGQGSDADTVLGLEAGANDYVVKPFKFAVLLARIRAH
LRQYEASEDAVFQVGPYTFHPGSKLLVSEKGSKTKLTEKETAILRFLYRAGRKPIAREVL
LQEVWGYNSQVTTHTLETHIYRLRQKIEPDPGNARLLVTDAGGYRLNP