Protein Info for ABIE41_RS04580 in Bosea sp. OAE506

Annotation: Ku protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 TIGR02772: Ku protein" amino acids 4 to 257 (254 residues), 312 bits, see alignment E=1.7e-97 PF02735: Ku" amino acids 13 to 194 (182 residues), 147.4 bits, see alignment E=2.4e-47

Best Hits

Swiss-Prot: 44% identical to KU_BRASO: Non-homologous end joining protein Ku (ku) from Bradyrhizobium sp. (strain ORS 278)

KEGG orthology group: None (inferred from 64% identity to mlo:mll4607)

Predicted SEED Role

"Ku domain protein" in subsystem DNA Repair Base Excision

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (301 amino acids)

>ABIE41_RS04580 Ku protein (Bosea sp. OAE506)
MAPRPAWKGYLKLSLVSCAVELTGTTDHSEKVSFRIINRKTGHTVKRQYVDGVTGKPVED
DDEVKGYEIGDDEYLLVEEDEIDAVQIESSHTLSIEHFVDRADIPQIYFDTPYYVTPSDD
VSEEAFAVIREAMARQKKAGIARIVLYRRERPVMIEPFDKGLLLTTLRYDKTVRKPDEIF
SDLGKPKIDSELIDLATHIIDKKQAAFDPSGFEDRYESALLELIQAKQKGKKPPVVQAAE
RPANVVNLFEALKKSLAGDDGAGAGKPAPSKGKKAADEPAPAKSSARAKSAAKPARTKKS
A