Protein Info for ABIE41_RS04310 in Bosea sp. OAE506

Annotation: 2'-deoxycytidine 5'-triphosphate deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF06559: DCD
  • amino acids 6 to 360 (355 residues), 571.1 bits, E=4.1e-176

Best Hits

KEGG orthology group: K01494, dCTP deaminase [EC: 3.5.4.13] (inferred from 75% identity to mno:Mnod_7450)

Predicted SEED Role

"Deoxycytidine triphosphate deaminase (EC 3.5.4.13)" (EC 3.5.4.13)

MetaCyc Pathways

• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (12/14 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis II (5/7 steps found)

KEGG Metabolic Maps

• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.13

Protein Sequence (362 amino acids)

>ABIE41_RS04310 2'-deoxycytidine 5'-triphosphate deaminase (Bosea sp. OAE506)
MLTLQPGIQPDHCIRAFVEAGAIRLAQPPAEGQIQPASLDLRLGEKAYRVRASFLPGPDR
TVRRRLDDLALHEIDLTRGAVLETGCVYIAELMEGLKLPAGLRAAANPKSSTGRLDVFTR
IITDCAREFDLVEDGYEGPLFIEISPRTFPVLVRSGSRLSQIRFRAGETKLDDTALGELH
KRETLVTAAEPSFQGGVAVSVDLSGFDGLIGYRGKHHTALIDVDRVGAYRASEFWEPIAS
DGSRALILDPGQFYILASKEAVHVPPDFAAEMTPFDALVGEFRVHYAGFFDPGFGHSGAG
GQGARAVLEVRSRDVPFIIEDGQIVGRLVYEAMASRPAALYGAGLKSNYQGQALKLSKHF
HD