Protein Info for ABIE41_RS04005 in Bosea sp. OAE506

Annotation: membrane protein insertase YidC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 624 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 366 to 384 (19 residues), see Phobius details amino acids 390 to 410 (21 residues), see Phobius details amino acids 456 to 480 (25 residues), see Phobius details amino acids 514 to 532 (19 residues), see Phobius details amino acids 552 to 573 (22 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 5 to 388 (384 residues), 320.3 bits, see alignment E=2.4e-99 PF14849: YidC_periplas" amino acids 91 to 379 (289 residues), 267.6 bits, see alignment E=2e-83 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 389 to 587 (199 residues), 219 bits, see alignment E=5.7e-69 PF02096: 60KD_IMP" amino acids 390 to 587 (198 residues), 203.2 bits, see alignment E=2.6e-64

Best Hits

Swiss-Prot: 63% identical to YIDC_METRJ: Membrane protein insertase YidC (yidC) from Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 63% identity to mrd:Mrad2831_3503)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (624 amino acids)

>ABIE41_RS04005 membrane protein insertase YidC (Bosea sp. OAE506)
MKEDNRNLLLAITLSVVVLFGWQYFYGVPQMEKQKQIAQQNQQAQSQTAPVPAPGSAPAP
AAAPGQTVAPAVAPATGVAVTRDQALAQSPRVRIETPKIAGSIALTGARLDDVSLKAYRE
TVDPNSPIIVLLSPLGGPNGYYSDFGWVAAPGAAVSLPNATTVWTADAQVLTPAKPLTLT
WDNGQGLLFRRVVTVDDNAMFQIRDEVDNKGSAPVSLFPYAQVVRHGRPATLGYYVLHEG
LIGYVGDHGLQEFTYDHVDKEPLLSPGTNGRVWKDAVGGFVGITDKYWAAAVVPDQSRKY
DGRFSSVQTGAARTYQADFLSEAVTVAPGASATSTARLFAGAKEVAAISGYETNLGIKRF
DLMIDWGWFYFFTKPMFFLLDWIFKHVGNFGVAILIVTLLLKGVFFPLASKSYASMAKMK
ALQPEMLALRERYADDKMKQQQALMELYKTQKINPLAGCWPVLVQIPVFFALYKILFITI
EMRHAPFFGWIRDLAAPDPTNLFNLFGLLPFTPPSILHLGLWPIIMGITMFVQMKMNPEP
PDPVQKMMFTWMPVFFTFLLGSFPAGLVIYWSWNNLLSVMQQGYIMRKHGVKIELFDNIK
SMFGKKPEPAPATAPAKPANSNKK