Protein Info for ABIE41_RS03665 in Bosea sp. OAE506

Annotation: leucyl aminopeptidase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 PF21337: Peptidase_M17_N_1" amino acids 13 to 131 (119 residues), 69.2 bits, see alignment E=3.4e-23 PF00883: Peptidase_M17" amino acids 148 to 436 (289 residues), 328.2 bits, see alignment E=5.5e-102

Best Hits

KEGG orthology group: K01255, leucyl aminopeptidase [EC: 3.4.11.1] (inferred from 64% identity to met:M446_6389)

Predicted SEED Role

"Peptidase B (EC 3.4.11.23)" (EC 3.4.11.23)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.1

Use Curated BLAST to search for 3.4.11.1 or 3.4.11.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (461 amino acids)

>ABIE41_RS03665 leucyl aminopeptidase family protein (Bosea sp. OAE506)
MNSLVSAASSDAIPLHCVTKAGLRALLADLAPESRRFAEAQGFAAQPGQHLLLPDGTGAV
VAVLLGVEGPEARRRDPFAPGRLAAVLPAGDYVLSGETGDPDLAALGWLLQVYRFDRYRK
PVSPAARLVLPEGVDGADLVRVAESVALARDLVNTPANDMGPAEIEAAIRALAGETGALV
TAILGDDLLARNFPMIHAVGRASPRPPRLVDLVWGDPGHPLVTLVGKGVAFDTGGLDLKP
SAGMLLMKKDMGGAAAAIAAARMIMLAKLPVRLRLLVPAVENAVAGASFRPGDVLPSRKG
LSVEIGNTDAEGRLILADALALADEEAPELLIDFATLTGAARTALGPELPPFYTHDEGLA
SEIARLGQAVNDPVWRMPLWPPYERMLDSRIADLNNVSGGSFAGSVTAALFLNRFVEKTA
SYAHFDIYAWNPSARPGRPEGGECQAARLVYALVKQLHPPG