Protein Info for ABIE41_RS01700 in Bosea sp. OAE506

Annotation: chemotaxis protein CheA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 694 PF01627: Hpt" amino acids 8 to 97 (90 residues), 56.3 bits, see alignment E=6.4e-19 PF02895: H-kinase_dim" amino acids 304 to 361 (58 residues), 50.2 bits, see alignment 5.9e-17 PF02518: HATPase_c" amino acids 411 to 548 (138 residues), 61.9 bits, see alignment E=1.5e-20 PF01584: CheW" amino acids 554 to 679 (126 residues), 101.2 bits, see alignment E=7.8e-33

Best Hits

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (694 amino acids)

>ABIE41_RS01700 chemotaxis protein CheA (Bosea sp. OAE506)
MMELDPTETFRQEASELLDSLESVLLDLGQSPQNRDLIDAAFRALHTIKGSGAMFGFDKV
AAFTHDFETAFDLIRKGKIDANHEIVTVSLSARDYIRTLIEDPDSTDPIIGEAIVEELQR
LIGAGPAGKKAAPAAEAPSDEAPADEAAAGWRIAIAFEPGILRNGTNPLVLLDDLRALGP
CTVEADTAAIPVLGELDPQTCLITWTVTLESACSQDEIEDVFMFVRDEMKLVITPLAEAG
KGGFGLDMSMPGDVAPAAAEPVKAEPVKAEAAPAPVARAAAPAPAAPAPEKAELNRRAED
KGNTTVRVQAERLDELMDRVGELVIAQARLSQIAHSGTDLAIKAIAEEIERLASGLRDST
MGVRMVPMGSLFARFRRLVHDLSRDLGKPVDFVTVGEDTEMDKTMIERLADPLVHLIRNA
IDHGIESAQDRATTSKSPTGRIELAARYVGAQVLVTVQDDGAGLNTARIRAKAEENGLIA
PGANLSEHEIHQFLFHPGFSTAKTISALSGRGVGMDVVKRTIEAMRGTIDLTTIPGHGSS
VTLRLPLTLAIIDGLLIRVGEARYIIPLSAVEECIELTAADEARAKGRSFLNVRGDLVPF
LRLRDLFESDGQPDPHQKVIVTSIGDTRVGLVVDQIIGSHQTVIKSLSKLHADVTMFSGA
TILGDGSAALILDVAQLVTLGQSRAESDRTPEAA