Protein Info for ABIE41_RS01285 in Bosea sp. OAE506

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 273 to 294 (22 residues), see Phobius details PF02743: dCache_1" amino acids 33 to 247 (215 residues), 71.5 bits, see alignment E=7.6e-24 PF07536: HWE_HK" amino acids 364 to 443 (80 residues), 63.5 bits, see alignment E=2.5e-21

Best Hits

KEGG orthology group: None (inferred from 48% identity to rec:RHECIAT_PC0000067)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (560 amino acids)

>ABIE41_RS01285 sensor histidine kinase (Bosea sp. OAE506)
MKKRLFLLATAALAPGVALLAINELTYRAEREREVHRLAQQASRQAAFELERIIEGMDGL
LIAVAANAAVSRDDPAGCSRALAAVAASVPSIRVISLMSVEGSVICDSMGSPAGQDLSDR
SYLRDALLADRTVVGEYTQSRITGTPVLPLARAVRDGKGEVRAVLATGIRLDWLGERLRE
RGVTPSGALTVADRNGVILARHPAPERFVGTRIPEAFQHLVRAPQPGSLDLVSQDGEARI
VGYQPIGAAPQALYVSAGLARSQAFAALNRSSLMGAIIVGLGAVLAFAAAWFVGNAFVRR
PIMKINEVLTAWRNGESHRRTGMRVSQGELESVGHAVDDMLDELTRRDEAATRAREQRDL
LTGELGHRVKNLLTVLQAIARQTFGTYVDAERSRIFSDRVVALSSALDVLLSDEQRESSI
AEVVATTLRPHVDRMSRIRTSGPPVRLESKTALALSMIVHELSTNALKYGALRDEVGMVT
IEWNRDEDGRVEFVWQEAGGPPVVPPERQGFGSRLIRHALPAECDPHIEIDFRPEGVVMQ
LSFDTGRSGLSGQQQAAAAG