Protein Info for ABIE41_RS01045 in Bosea sp. OAE506

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 555 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 273 to 294 (22 residues), see Phobius details PF02743: dCache_1" amino acids 32 to 248 (217 residues), 72.6 bits, see alignment E=3.4e-24 PF07536: HWE_HK" amino acids 364 to 443 (80 residues), 58 bits, see alignment E=1.3e-19

Best Hits

KEGG orthology group: None (inferred from 45% identity to rlt:Rleg2_4826)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (555 amino acids)

>ABIE41_RS01045 sensor histidine kinase (Bosea sp. OAE506)
MKKRLFLLATAALTPGAALLGINEVTYRAEREQEVHRMAQQASRQAASELERIIEGIDGL
LIAVAANAEVSETDPSACSRALAAVAASVSSVRVIFLMSVEGRIVCDSVGASLGHDLSDR
GYLQEALVSDRTAVGEYTHSRITDTAVLPLARAVRDARGEVRGVLATGIRLDWLGERLRE
RGVTPSGALTVADRKGVILARYPLPERFVGTRIPAAFRHLLRGPKPGSIDLTSQDGEARI
VGYQPVGMPLQGLYVSAGLARSEAFAALNRSSLIGGIIVGFGALLTFAAAWFVGNAFVRR
PIMQINQVLASWRHGESRHRTGMRGSQGEIESVGHAVDDLLDELAVREEAAIRAREQRDL
ATRELAHRVKNLLTVLQAIARQTFGPYVDAERSQIFSDRVVALSAALDVLLSDEDRQGAI
GDIIATTLRPHVDRLSRISSSGPIVRLEGKMGLALSMIVHELATNALKYGALKDEEGRVE
IHWDLDAEGRITLLWRECDGPPVLPPDRQGFGSRLIRRALPAECDPQVELDFPPTGLVLR
LSFNTESRRPTDAAG