Protein Info for ABIE41_RS00895 in Bosea sp. OAE506
Annotation: SDR family oxidoreductase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 52% identical to YHDF_BACSU: Uncharacterized oxidoreductase YhdF (yhdF) from Bacillus subtilis (strain 168)
KEGG orthology group: K00540, [EC: 1.-.-.-] (inferred from 84% identity to rsq:Rsph17025_2997)MetaCyc: 47% identical to aldehyde reductase (chloroplastic) (Arabidopsis thaliana col)
Aldehyde reductase. [EC: 1.1.1.21]; Alcohol dehydrogenase (NADP(+)). [EC: 1.1.1.21, 1.1.1.2]; 1.1.1.2 [EC: 1.1.1.21, 1.1.1.2]; 1.1.1.- [EC: 1.1.1.21, 1.1.1.2]; 1.1.1.- [EC: 1.1.1.21, 1.1.1.2]
Predicted SEED Role
"Short-chain dehydrogenase/reductase SDR"
MetaCyc Pathways
- superpathway of methylglyoxal degradation (6/8 steps found)
- methylglyoxal degradation III (1/2 steps found)
- pyruvate fermentation to butanol I (4/8 steps found)
- D-xylose degradation to ethylene glycol (engineered) (1/4 steps found)
- L-tryptophan degradation X (mammalian, via tryptamine) (1/4 steps found)
- superpathway of Clostridium acetobutylicum solventogenic fermentation (7/13 steps found)
- glycerol degradation to butanol (9/16 steps found)
- detoxification of reactive carbonyls in chloroplasts (4/10 steps found)
- superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation (9/17 steps found)
- traumatin and (Z)-3-hexen-1-yl acetate biosynthesis (3/12 steps found)
- superpathway of lipoxygenase (4/22 steps found)
- superpathway of pentose and pentitol degradation (11/42 steps found)
KEGG Metabolic Maps
- Alkaloid biosynthesis I
- Caprolactam degradation
- Carotenoid biosynthesis - General
- Fructose and mannose metabolism
- Galactose metabolism
- Glycerolipid metabolism
- Glycolysis / Gluconeogenesis
- Insect hormone biosynthesis
- Nucleotide sugars metabolism
- Pentose and glucuronate interconversions
- Porphyrin and chlorophyll metabolism
- Puromycin biosynthesis
- Pyruvate metabolism
- Trinitrotoluene degradation
- alpha-Linolenic acid metabolism
Isozymes
Compare fitness of predicted isozymes for: 1.-.-.-
Use Curated BLAST to search for 1.-.-.- or 1.1.1.2 or 1.1.1.21
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (286 amino acids)
>ABIE41_RS00895 SDR family oxidoreductase (Bosea sp. OAE506) MSDTHPTPPFADQQQPMPGLTERMEPVPDHGETSYRGSGRLAGKKAVITGGDSGIGRAVA LAYAREGADVLVSYLNEDEDARETARLIEEAGRKAVLVAGDLQEASHCRAVIDRAVSELG GIDILVNNAAHQASFGDIGEISDEEWELTFKVNIHAMFYLTKAAVPHMPAGSAIINTASI NADTPSPHLLAYATTKGAIQNFTAGLAQLLAEKGIRANAVAPGPVWTPLIPSTMPAEAVK NFGKQVPMQRPGQPAELATAYVMLAEPLSSYVSGATIAVTGGKPIL