Protein Info for ABIE41_RS00175 in Bosea sp. OAE506

Annotation: peptide deformylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 193 PF01327: Pep_deformylase" amino acids 4 to 178 (175 residues), 176.6 bits, see alignment E=1.4e-56 TIGR00079: peptide deformylase" amino acids 89 to 184 (96 residues), 121.7 bits, see alignment E=1.1e-39

Best Hits

Swiss-Prot: 56% identical to DEF_NOVAD: Peptide deformylase (def) from Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)

KEGG orthology group: K01462, peptide deformylase [EC: 3.5.1.88] (inferred from 61% identity to sno:Snov_0057)

Predicted SEED Role

"Peptide deformylase (EC 3.5.1.88)" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Conserved gene cluster associated with Met-tRNA formyltransferase (EC 3.5.1.88)

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.88

Use Curated BLAST to search for 3.5.1.88

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (193 amino acids)

>ABIE41_RS00175 peptide deformylase (Bosea sp. OAE506)
MAIRPLVILPDAQLRLVSTPVAEITPEIRTLVADMFETMYDAPGIGLAAIQIGVPWRVVT
LDVAKRAPEPAAEEEPAEADTDGSQEKRDRQPRNPIAFINPEITWSSEERSVYEEGCLSI
PEYYEEVERPASVRVAYTDLDGKRQEIEADGLLATCIQHEIDHLNGVLFIDHLSRLKRER
VTKRFAKQARREG