Protein Info for ABIE40_RS30905 in Rhizobium sp. OAE497

Annotation: cbb3-type cytochrome c oxidase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 670 transmembrane" amino acids 16 to 36 (21 residues), see Phobius details amino acids 57 to 74 (18 residues), see Phobius details amino acids 102 to 126 (25 residues), see Phobius details amino acids 143 to 164 (22 residues), see Phobius details amino acids 188 to 212 (25 residues), see Phobius details amino acids 226 to 252 (27 residues), see Phobius details amino acids 274 to 298 (25 residues), see Phobius details amino acids 310 to 334 (25 residues), see Phobius details amino acids 341 to 366 (26 residues), see Phobius details amino acids 380 to 402 (23 residues), see Phobius details amino acids 415 to 439 (25 residues), see Phobius details amino acids 454 to 473 (20 residues), see Phobius details amino acids 493 to 517 (25 residues), see Phobius details amino acids 593 to 632 (40 residues), see Phobius details PF00115: COX1" amino acids 56 to 501 (446 residues), 467.3 bits, see alignment E=2.5e-144

Best Hits

Swiss-Prot: 70% identical to COX14_BRADU: Probable cytochrome c oxidase subunit 1 (blr2715) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K02298, cytochrome o ubiquinol oxidase subunit I [EC: 1.10.3.-] (inferred from 72% identity to mci:Mesci_6326)

MetaCyc: 63% identical to cytochrome bo3 subunit 1 (Escherichia coli K-12 substr. MG1655)
RXN-21817 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (670 amino acids)

>ABIE40_RS30905 cbb3-type cytochrome c oxidase subunit I (Rhizobium sp. OAE497)
MFGKLDLSAIPLSQPIPLITSAIVVVIGLAVAVLITTKKLWPYLWHEWITSVDHKRIGIM
YCLLGILMLIRGFADAIMMRTQQAVAINAEGYLPPEHYNQIFTAHGTIMILFGAMPLVLG
FMNFLVPLQLGVRDVAFPTFNSVGFWLTASGALLVNVSLLVGEFARTGWLPYPPLSETTY
SPGVGVDYYLWAVQISGIGTLITGINIVTTILKMRCPGMSYLRMPVFCWTALASCLLIVA
AFPILTATLAMLTLDRYVGWHYFTSMSGGNPMMFVNLIWAWGHPEVYILILPAFGIFSEI
FSTFSGKPLFGYRSMVAATLFICVVSMLVWLHHFFTMGAGAAVNTFFGISSSIIAVGTGV
KIYNWIFTMYGGRVRLEVPMLWSLGFIFTFILGGLTGVLLAIPPADFVTHNSMFLVAHFH
NVIIGGVVFGIFAGVEFWFPKAFGFRLHAGWGKAAFWLALFGFWVTFTPLYILGLDGMTR
RLQHINFEHWTPWLYVSVVGIAILIAGVVAQVLQLIVSIRNRDALRDVTGDPWDGRSLEW
ATASPPPFFNFAVTPNVEGEEAYWGIKLRAIETQQLSPEPHYEAIEMPINSPVGFYTAFF
ATVFGFAMIWYIWWLAALSLLAAFIGFVVFAWRDVHEFEVPEEEVERAERKRRAAREEFL
NRLAQEGGTA