Protein Info for ABIE40_RS30830 in Rhizobium sp. OAE497

Annotation: cytochrome c oxidase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 636 transmembrane" amino acids 49 to 69 (21 residues), see Phobius details amino acids 95 to 116 (22 residues), see Phobius details amino acids 128 to 147 (20 residues), see Phobius details amino acids 174 to 198 (25 residues), see Phobius details amino acids 210 to 234 (25 residues), see Phobius details amino acids 272 to 291 (20 residues), see Phobius details amino acids 298 to 318 (21 residues), see Phobius details amino acids 333 to 356 (24 residues), see Phobius details amino acids 366 to 388 (23 residues), see Phobius details amino acids 403 to 425 (23 residues), see Phobius details amino acids 437 to 459 (23 residues), see Phobius details amino acids 479 to 500 (22 residues), see Phobius details amino acids 588 to 605 (18 residues), see Phobius details amino acids 610 to 628 (19 residues), see Phobius details TIGR02891: cytochrome c oxidase, subunit I" amino acids 37 to 540 (504 residues), 727.7 bits, see alignment E=3.5e-223 PF00115: COX1" amino acids 45 to 488 (444 residues), 511.4 bits, see alignment E=1.1e-157

Best Hits

Swiss-Prot: 44% identical to COX1_BACPE: Cytochrome c oxidase subunit 1 (ctaD) from Bacillus pseudofirmus (strain OF4)

KEGG orthology group: K02274, cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 79% identity to rlg:Rleg_5827)

Predicted SEED Role

"Cytochrome c oxidase polypeptide I (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (636 amino acids)

>ABIE40_RS30830 cytochrome c oxidase subunit I (Rhizobium sp. OAE497)
MAEQHSPVVMDTDLDDAGLVHALDVTWGTRRGFWGAIATVDHKVIARRYIVTAFVFLMLG
GVLALAMRLQLAQPEARIIDPDRYNQIFTMHGSNMMFLFAVPVMEAMAVYLVPLMIGTRN
IAFPRLNAFSYWVFLAGGILLWLSFLLDAAPDVGWFAYVPLAGPEYGPGKRADIWAQMIT
FTELSALAIAVEIVVTVFTQRAPGMSLDRIPLFVWAMLVTAFLVIMAMPAIMFASSTLIM
DRLVGTHFYNPAEGGDALLYQHLFWFFGHPEVYIIFLPAVGMVSTILPTFVQRPVFGYLP
LVMALIATGILSFGLWVHHMFVVGLPRLGESFFTASSMAIALPAGIQIFCWLATIWAGRP
IFKVPMLFIIGFIVTFVIGGMTGVMVASVPFDTQVHDTYFVVAHFHYVLVGGAVFPLLAA
VYYWFPKMTGRMMSEVLGRWAFWLIFAGFHLTFFPMHILGLQGMPRRIYTYQPELPWSGL
NLFVSVSSIVLAAGFLIFFIDALRSWRSGQPAGDNPWNAPTLEWATSSPPPSPNFCFIPV
VGDRNPLWSTPGALAVASGLRVDRRELLVTSVVEALPQARESSARNSVWPFWAALATSVM
LVWSMFSPWAVIWGSMPIAVTLIGWFWPKGTPEDDS