Protein Info for ABIE40_RS28560 in Rhizobium sp. OAE497

Annotation: cytochrome c oxidase subunit II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 39 to 60 (22 residues), see Phobius details amino acids 81 to 102 (22 residues), see Phobius details TIGR02866: cytochrome c oxidase, subunit II" amino acids 31 to 226 (196 residues), 178.2 bits, see alignment E=7.3e-57 PF00116: COX2" amino acids 139 to 214 (76 residues), 72.6 bits, see alignment E=2.6e-24 PF00034: Cytochrom_C" amino acids 241 to 330 (90 residues), 46.2 bits, see alignment E=1e-15

Best Hits

KEGG orthology group: K02275, cytochrome c oxidase subunit II [EC: 1.9.3.1] (inferred from 84% identity to rlg:Rleg_5826)

Predicted SEED Role

"Cytochrome c oxidase polypeptide II (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (330 amino acids)

>ABIE40_RS28560 cytochrome c oxidase subunit II (Rhizobium sp. OAE497)
MTRPPIIGLSLASLCLSGCTGSQSALDAAGASASALKQLIILIVIVCAAVWLLVMLVLAW
SLLRSRDGRGTAGNDRTARKVVAAAVAATVFIIAGLTIASFYTTRQIGPSSKAALTVSVR
GQQWWWQFVYPASGSEAGFQTANELHIPVGKDVTLRLESVDVIHSFWVPSLAGKLDLIPG
RTNELTLHADRPGVYRGQCAEYCGLQHSHMALLVVAEDEENYKRWLQGQQRERLPPPDTE
IAAGEAVFLSKPCAACHTVRGTSAAGTTGPDLTHVGSRETIGAGLLPNTRGSLAAWIADP
QTLKPGNNMPVVPLSAEELKQVSAYLESLK