Protein Info for ABIE40_RS27980 in Rhizobium sp. OAE497

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 561 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 275 to 297 (23 residues), see Phobius details PF02743: dCache_1" amino acids 34 to 246 (213 residues), 65.4 bits, see alignment E=5.6e-22 PF07536: HWE_HK" amino acids 362 to 441 (80 residues), 67.3 bits, see alignment E=1.6e-22

Best Hits

KEGG orthology group: None (inferred from 68% identity to rlt:Rleg2_4826)

Predicted SEED Role

"FIG00986619: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (561 amino acids)

>ABIE40_RS27980 sensor histidine kinase (Rhizobium sp. OAE497)
MRLKLVAVAVAALAPVIAILAYNEVATRQARMSEVTAQASQAARQASSEVERIVEGVRSM
MVAVTSMPSVRHLDGPNCNDALKSLAENVPNIGTIFVLRPDGSPVCGSVGIPSSAAFGDR
EYFRKAVEAKNFVVGKYTKSRITGAAVLPMAMPLVEGDAVTAVVVSGIRLDWLQNRITER
GVAPGNAVTLADGHGTILARVPLPEQFVGTVIPDEYQNLIHADRPGVIEVKSQDGTERLL
GYRPISVPGSPIYVSAGVSVADAFAPINRATIANTLGIAAGAAVSLILALIIGNRFLLNP
ISRIADVMERWKSGEGAARTRMKPTDELHAVGATLDGLLDELDCRRVQNESSVQERTLLA
RELAHRVKNGFALVQAIARQTFGRADPERYQSFSERLAALAGTYDLLLSREGAASSMNDV
VAAALRAHLSEARRISVSGPDVPLSSDLALPLSLVLHELATNATKYGSLHVEGGSVAIDW
TEMDGRIDLCWREEGGPPVAAPTRKGFGSVLIERAFPSKANAVSKFQFRPEGLCFEISFD
LREPQQTGEVHGAAVGVRRNA