Protein Info for ABIE40_RS27645 in Rhizobium sp. OAE497

Annotation: bifunctional lysylphosphatidylglycerol flippase/synthetase MprF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 867 transmembrane" amino acids 29 to 46 (18 residues), see Phobius details amino acids 66 to 88 (23 residues), see Phobius details amino acids 100 to 125 (26 residues), see Phobius details amino acids 144 to 169 (26 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 223 to 244 (22 residues), see Phobius details amino acids 251 to 277 (27 residues), see Phobius details amino acids 280 to 281 (2 residues), see Phobius details amino acids 303 to 321 (19 residues), see Phobius details amino acids 343 to 362 (20 residues), see Phobius details amino acids 380 to 400 (21 residues), see Phobius details amino acids 410 to 429 (20 residues), see Phobius details amino acids 434 to 452 (19 residues), see Phobius details amino acids 464 to 486 (23 residues), see Phobius details amino acids 508 to 528 (21 residues), see Phobius details PF09924: LPG_synthase_C" amino acids 553 to 839 (287 residues), 322.4 bits, see alignment E=1.2e-100

Best Hits

KEGG orthology group: K14205, phosphatidylglycerol lysyltransferase [EC: 2.3.2.3] (inferred from 86% identity to rlt:Rleg2_3226)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 2.3.2.3

Use Curated BLAST to search for 2.3.2.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (867 amino acids)

>ABIE40_RS27645 bifunctional lysylphosphatidylglycerol flippase/synthetase MprF (Rhizobium sp. OAE497)
MASQNSLEEMESEEAGGFRGFLRRYRTQLVAAATLILFCMVGYAIMQLTDEVRYDDVVEA
LADTRVSSILLALLFTGLSFFALIFYDLNAIDYIGKKLPFPHVALTAFSAYAVGNTAGFG
ALSGGAIRYRAYSRLGLTPEDIGRVIAFVTLSFGLGLASVAAIALMIIADEIGPLINTNA
LLLRIIAGAILAGLGFVVYLGRDGRAVNLGPIAVRLPDSRTWSRQFLVTAFDIAASATVL
YVLLPQTAISWPVFLAVYAIAVGLGVLSHVPAGLGVFETVIIASLGSAVNIDAVLGSLVL
YRLIYHVLPLLIAVLAVSLTELRRFVDHPAASSIRRIGGRLTPQLLSAFALILGVMLIFS
SVTPTPDENLEFLANYLPLPIVEGAHFLSSLFGLALVVAARGLGQRLDGAWLVSVVSAVL
ALALSLLKAIALVEAIFLAILIFSLFVSRRLFTRHASLLNQTLTAAWLMAIAVICVGAVV
ILLFVYRDVEYSNELWWQFEFAAEAPRGLRAVLGITIISSAIAIFSLLRPATFRPEPATE
EALQRAVDIVKAQDYADANLVRMADKSIMFSEKGDAFIMYGRQGRSWIALFGPIGNQEAA
PELVWSFVEAARAAGCRAVFYQISPGLLSHCADAGLRAFKLGELAVADLGAFEMKGGKWA
NLRQTASRAQRDGLSFEVIPADGVPAILGDLSVVSSSWLEDHNAKEKGFSLGAFEPDYVN
SQPVGVLKKDGKIVAFANILVTETKSEGTIDLMRFSPEAPKGSMDFLFVQIMEYLRAEGY
KHFNLGMAPLSGMSKRETAPVWDRIGSTVFEHGERFYNFKGLRAFKSKFHPHWQPRYLAV
SGGGNPMIALMDATFLIGGGLKGVVRK