Protein Info for ABIE40_RS26135 in Rhizobium sp. OAE497

Annotation: cation-translocating P-type ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 762 transmembrane" amino acids 122 to 143 (22 residues), see Phobius details amino acids 155 to 175 (21 residues), see Phobius details amino acids 187 to 208 (22 residues), see Phobius details amino acids 215 to 233 (19 residues), see Phobius details amino acids 369 to 390 (22 residues), see Phobius details amino acids 397 to 425 (29 residues), see Phobius details amino acids 695 to 714 (20 residues), see Phobius details amino acids 717 to 735 (19 residues), see Phobius details PF00403: HMA" amino acids 40 to 103 (64 residues), 42.1 bits, see alignment E=1.4e-14 TIGR01511: copper-translocating P-type ATPase" amino acids 171 to 737 (567 residues), 547.4 bits, see alignment E=8.7e-168 TIGR01525: heavy metal translocating P-type ATPase" amino acids 189 to 737 (549 residues), 543.7 bits, see alignment E=1.2e-166 TIGR01512: cadmium-translocating P-type ATPase" amino acids 220 to 737 (518 residues), 374.3 bits, see alignment E=1.8e-115 TIGR01494: HAD ATPase, P-type, family IC" amino acids 223 to 719 (497 residues), 218.2 bits, see alignment E=3.2e-68 PF00122: E1-E2_ATPase" amino acids 254 to 430 (177 residues), 161.9 bits, see alignment E=1.8e-51 PF00702: Hydrolase" amino acids 447 to 649 (203 residues), 98.9 bits, see alignment E=7.6e-32

Best Hits

Swiss-Prot: 78% identical to FIXI_RHILV: Nitrogen fixation protein FixI (fixI) from Rhizobium leguminosarum bv. viciae

KEGG orthology group: None (inferred from 78% identity to rlt:Rleg2_5022)

Predicted SEED Role

"Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4)" (EC 3.6.3.4)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.4

Use Curated BLAST to search for 3.6.3.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (762 amino acids)

>ABIE40_RS26135 cation-translocating P-type ATPase (Rhizobium sp. OAE497)
MTCCAIDADGVMAMSTTAFSAEEIALASHPLGGGLHQLDLSVPDVHCGACISTIEKALTA
LPFVSKARVNLTARRVTCVYTEKAGGRAADPTQIITAVGGAGYRAHLYAPLASECDKTRN
QLLLAVGVAGFAATNIMLLSVSVWSGADAATRDMFHWISAMIAAPALIYSGRFFFQSAWN
ALRHSRTNMDVPISLAVTLSYFVSLWETMHHGEHAWFDATVSLLFFLLIGRTLDHVMREK
ARAAINGLARIAPRGALLIQPDGSHRYVAVEEISVGDEIAVAAGDRIPVDGVVVSGQSDL
DLSIVTGESSPVSVRTGQPVSSGSMNLTGSLAVRATRLARDSLLAEIIGLMEAAEGGRAR
YRRIADRAAALYSPVVHLLALASFLGWGFIGGDWKQAMLVAVAVLIITCPCALGLAVPVV
QVVAAGELFRRGIMVKDGSALERLAEIDTVAFDKTGTLTIGRPRLVAANATDPADIVRAA
ALAGHSRHPLSQALARTGTSDAAAFEQIMEIPGGGLEARHAGALYRLGSEAFACGGTEAP
LTNEGPYSEVVFSRDGQAIARFFFDDTLRPGAAEAVTELRKAGFATAILSGDRQSVVDNT
ARALGIGHALGGLTPGEKVGECQALNGNSHRVFMVGDGINDAPALAAAHVSMAPATASDI
GRQAADLVFFNDRLDAVPVAIAVARRSAALIRQNFALAIGYNVLAVPIALAGLATPLIAA
VAMSTSSIIVVSNALRLNAFGKGAAANDRPAPAAARAEARAA