Protein Info for ABIE40_RS24975 in Rhizobium sp. OAE497

Annotation: HAMP domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 455 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 152 to 176 (25 residues), see Phobius details PF00672: HAMP" amino acids 174 to 226 (53 residues), 22.5 bits, see alignment 1.8e-08 PF00512: HisKA" amino acids 232 to 297 (66 residues), 29.9 bits, see alignment E=7.1e-11 PF02518: HATPase_c" amino acids 342 to 448 (107 residues), 73 bits, see alignment E=4.2e-24

Best Hits

KEGG orthology group: None (inferred from 61% identity to rle:RL1156)

Predicted SEED Role

"FIG00987019: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (455 amino acids)

>ABIE40_RS24975 HAMP domain-containing sensor histidine kinase (Rhizobium sp. OAE497)
MRLASLRRSTPFRLAMTFGVLFILTFVVSGAVMYHMLRTGLAHEMDASLQEMNSVIASTY
APDDMEDLIATLNSYVNLQTTKDGLYSLVDARGNRLAGNFTAIKMPPGVYTINPEDIGQP
GSGRFRIQVTELGPNLLVVGESFSDMDDLLKIVLVSLGWAALLVVVAALGGGIFLAARAQ
HRLDAVARTMLDVSNGWLESRIPLKGKSDDLDLVAMQINSALDRLSGLVEGMRQVSADIA
HELKTPLNRLKMTLGDAIEGAAGGRDVGSLLADARAESDQINATFEALLRISQIEAGARR
QRFQKVDLAGILTFVEEVYASVAEDNGQMLELLPSPSVEIMGDRELLTQMVVNLVENAIT
HCPEGTRIGMALLQADGETVLRVVDNGAGIPSDERDNVFRRLYRMDKSRTTSGSGLGLTL
VRAIADLHFAHIELGDNRPGLAVAVSFPDPPPSAG