Protein Info for ABIE40_RS24620 in Rhizobium sp. OAE497

Annotation: potassium-transporting ATPase subunit KdpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 695 transmembrane" amino acids 35 to 52 (18 residues), see Phobius details amino acids 64 to 83 (20 residues), see Phobius details amino acids 219 to 243 (25 residues), see Phobius details amino acids 250 to 275 (26 residues), see Phobius details amino acids 600 to 621 (22 residues), see Phobius details amino acids 629 to 647 (19 residues), see Phobius details amino acids 667 to 692 (26 residues), see Phobius details TIGR01497: K+-transporting ATPase, B subunit" amino acids 4 to 690 (687 residues), 1020.1 bits, see alignment E=0 TIGR01494: HAD ATPase, P-type, family IC" amino acids 72 to 339 (268 residues), 109.1 bits, see alignment E=1.9e-35 amino acids 425 to 614 (190 residues), 145.8 bits, see alignment E=1.4e-46 PF00122: E1-E2_ATPase" amino acids 104 to 283 (180 residues), 110.4 bits, see alignment E=7.9e-36 PF00702: Hydrolase" amino acids 300 to 543 (244 residues), 85.6 bits, see alignment E=6.3e-28

Best Hits

Swiss-Prot: 89% identical to KDPB_AGRFC: Potassium-transporting ATPase ATP-binding subunit (kdpB) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K01547, K+-transporting ATPase ATPase B chain [EC: 3.6.3.12] (inferred from 91% identity to rle:pRL110380)

Predicted SEED Role

"Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (695 amino acids)

>ABIE40_RS24620 potassium-transporting ATPase subunit KdpB (Rhizobium sp. OAE497)
MSQAKSASILDSRILIPAIGAAFTKLNPRTLAKNPVMFVVATVSALTTVLFLRDVATGGG
NLGFSFQINLWLWFTVLFANFAEAVAEGRGKAQADSLRKARTETQAKLLTANNGSGYRMV
PGTSLKVGDLVLVEAGDIIPSDGEVVEGVASVNEAAITGESAPVIRESGGDRSAVTGGTQ
VLSDVIRVRITAAAGSTFIDRMIALVEGAERQKTPNEIALNILLAGMTLIFVLATATIPS
FAAYAGGSIPIIVLVALFVTLIPTTIGALLSAIGIAGMDRLVRFNVLAMSGRAVEAAGDV
DTLLLDKTGTITLGNRQATSFRPVRGITEQELADAAQLASLADETPEGRSIVVLAKEKYA
IRGRDMGSLQATFVPFTAQTRMSGVDVGGSSIRKGAVDAVLAYVGANNAPSNGNAAIALR
PETDVIRELQAIADEIAKAGGTPLAVARDGKLLGVIQLKDIVKGGIRERFAELRRMGIRT
VMITGDNPMTAAAIAAEAGVDDFLAQATPENKLSLIREEQAKGKLVAMCGDGTNDAPALA
QADVGVAMNTGTVAAREAGNMVDLDSDPTKLIEIVEIGKQLLMTRGALTTFSIANDIAKY
FAIIPAMFLTFYPQLGVLNIMGLATPQSAILSAIIFNALIIVALIPLSLKGVKYRAIGAG
ALLSRNLLIYGLGGIVVPFIGIKAIDMVITAIGLA