Protein Info for ABIE40_RS24580 in Rhizobium sp. OAE497

Annotation: sulfate ABC transporter permease subunit CysW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 transmembrane" amino acids 24 to 49 (26 residues), see Phobius details amino acids 70 to 96 (27 residues), see Phobius details amino acids 115 to 135 (21 residues), see Phobius details amino acids 146 to 166 (21 residues), see Phobius details amino acids 252 to 272 (21 residues), see Phobius details TIGR00969: sulfate ABC transporter, permease protein" amino acids 20 to 279 (260 residues), 324.8 bits, see alignment E=4.7e-101 TIGR02140: sulfate ABC transporter, permease protein CysW" amino acids 23 to 280 (258 residues), 414.2 bits, see alignment E=2.3e-128 PF00528: BPD_transp_1" amino acids 86 to 280 (195 residues), 49.3 bits, see alignment E=2.5e-17

Best Hits

Swiss-Prot: 57% identical to CYSW_SYNY3: Sulfate transport system permease protein CysW (cysW) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K02047, sulfate transport system permease protein (inferred from 90% identity to rlg:Rleg_6757)

MetaCyc: 53% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysW (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysW" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (290 amino acids)

>ABIE40_RS24580 sulfate ABC transporter permease subunit CysW (Rhizobium sp. OAE497)
MALDTATAAPKVRSVVTESRLARWSLIFLSLLFLLLMVFLPLAAVFVEAFRKGVVAFFEA
LQDAETFSAIRLTLIVAGISVPLNLVFGVAAAWAIAKFEFKGKAFLTTLIDLPFSVSPVI
SGLVFVLLFGANTYLGKWLDAHSIKILFAVPGLVLATMFVTFPFVARELIPLMQEQGTAD
EEAALSLGASGWQTFWHVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGQTNTMP
LQVEILYNEYNFTGAFAVATLLALLALVTLVLKTLLEMRYSAEIAASRRH