Protein Info for ABIE40_RS23175 in Rhizobium sp. OAE497

Annotation: FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 853 PF01266: DAO" amino acids 9 to 382 (374 residues), 139.1 bits, see alignment E=5.4e-44 PF16350: FAO_M" amino acids 385 to 441 (57 residues), 48.8 bits, see alignment 1.4e-16 PF01571: GCV_T" amino acids 443 to 722 (280 residues), 186.3 bits, see alignment E=1.3e-58 PF08669: GCV_T_C" amino acids 791 to 837 (47 residues), 35.4 bits, see alignment 1.6e-12

Best Hits

KEGG orthology group: None (inferred from 94% identity to rle:pRL110236)

Predicted SEED Role

"Sarcosine oxidase alpha subunit (EC 1.5.3.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (EC 1.5.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.5.3.1

Use Curated BLAST to search for 1.5.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (853 amino acids)

>ABIE40_RS23175 FAD-dependent oxidoreductase (Rhizobium sp. OAE497)
MAEFPSKAKVVIIGLGGIVGASIAHHLIERGWDDIVGIDKSGIPTDIGSTAHASDFCYTT
SHDYLSVWTTQYSIDFYEKMGHYARIGGLEVARTGDDTWMEEIKRKLSSAKAFGTNARYV
SPSEIKEMFPLIEEDQVQGGMFDPDAGLVIPRSQTVAGKLVDAAEKSGKLKMFGNTPAKS
LIVEGGRIKGVVTHRGTIMADHVIVCAGLWGRLIAEMVGEDLPVMPVDHPLTFFGPYNEF
EGTGKEIGFPLLRDQGNSAYMRDTGDPATTEGGQIEWGYYETTNPRMCHPRDLLEKHEAR
LSPSQRDLEMEQIIEPLERAMELTPILGELGYNEGHSFNGLLQVSAGGGASCGESQKVRG
LWYCVAIWVKDGPGYGKLIADWMTDGRTEIDHNSIDYARFYPHQLTEEFIEGRCYEAAQK
IYFPAVHTREPYASGRNAKRSPFYEREKELGGYFMELGGWERAHGYAANEHLLEKYADRV
PVRENEWDNRHFWRVSNAEHLAMSEDCGIVNLSHFHMVDIEGPDHVDLLEWLCAAKIGGD
ANIGKGIYTHFLDDEGMVRADFTVIRMADRCRLINGADAGPRDFHYMKRVAEDRGLDVTI
TDVSEKYITIGIWGPNARDTLKKVVADPSGLDAENFAFAAIKPIEIGGKPVTAFRISYVG
EQGWELHMKYEDGLAVWDTLRSTGVMPFGVETYANSRRMEKSLRLQNGDLLTQYNLLEAD
LARPKVKESDFRGKAKHLEYKAREHQPAMLCTLVMTENTDKSGVKRYPVGSMPVMDPETG
KVLIDELGRRSYTTSVAFGPTLGKNIALAYLPWDYCQVGRKLNIEYFAEIYPVEVAAVGY
KPLYDPENLNPRS