Protein Info for ABIE40_RS20720 in Rhizobium sp. OAE497

Annotation: DegQ family serine endoprotease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 497 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details TIGR02037: peptidase Do" amino acids 50 to 491 (442 residues), 510.4 bits, see alignment E=2.2e-157 PF00089: Trypsin" amino acids 94 to 270 (177 residues), 71.6 bits, see alignment E=2.6e-23 PF13365: Trypsin_2" amino acids 113 to 247 (135 residues), 131.6 bits, see alignment E=1.2e-41 PF00595: PDZ" amino acids 280 to 343 (64 residues), 27.3 bits, see alignment E=1.1e-09 amino acids 416 to 481 (66 residues), 39.6 bits, see alignment E=1.6e-13 PF13180: PDZ_2" amino acids 286 to 377 (92 residues), 56.7 bits, see alignment E=7.6e-19 amino acids 400 to 491 (92 residues), 49.7 bits, see alignment E=1.1e-16 PF17820: PDZ_6" amino acids 313 to 366 (54 residues), 41.4 bits, see alignment 3.1e-14 amino acids 427 to 483 (57 residues), 45.1 bits, see alignment 2.1e-15

Best Hits

Swiss-Prot: 45% identical to DEGPL_PSEMY: Probable periplasmic serine endoprotease DegP-like (Pmen_1471) from Pseudomonas mendocina (strain ymp)

KEGG orthology group: K01362, [EC: 3.4.21.-] (inferred from 80% identity to rlt:Rleg2_0763)

Predicted SEED Role

"HtrA protease/chaperone protein"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (497 amino acids)

>ABIE40_RS20720 DegQ family serine endoprotease (Rhizobium sp. OAE497)
MSKILLKHRTAALLGAALIAGTAALPFTINAATAVAAPAEIGGTLASGGSFAPIVDADKP
AVVTVTTTMKATDASDQQSPMDEQFRQFFEQQGIPFPHQAPKNEGGQHAMALGSGFIISP
DGVIVTNNHVIDNAMDIKVTLDDGTELPAKLVGTDPKSDIAVLKIQAPKPLATVAWGDSD
KLKLGDQILAIGNPFGIGTTVTAGIVSARGRDLHSGPYDDFIQIDAPINHGNSGGPLVDR
DGHVVGINTAIYSPNGGSVGVGFAIPSDEAKMIVAKLQKDGSIEHGYLGVQIQAVTKDVA
DAVGLSDAQGALVAAVSGDTPAARAGIKTGDIVTAVGGEAVKTPKDLSRLVADMSPGAKQ
TMTVWRDGKSTDLNVTIGGNDDGQKQAAADESDGKTQSGPSIGVGLADLTPDARQELNLP
RSINGAVVASVNPDKPAAAAGIQTGDVIVSVNDKPVHDASDAKAAVASAAKSGRKSVLLL
IERGGNKTFVAVPFSAA