Protein Info for ABIE40_RS20580 in Rhizobium sp. OAE497

Annotation: transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 377 PF13458: Peripla_BP_6" amino acids 5 to 342 (338 residues), 174.7 bits, see alignment E=4.5e-55 PF13433: Peripla_BP_5" amino acids 5 to 363 (359 residues), 331 bits, see alignment E=1e-102

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 83% identity to rlg:Rleg_6672)

Predicted SEED Role

"ABC-type branched-chain amino acid transport systems, periplasmic component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (377 amino acids)

>ABIE40_RS20580 transporter substrate-binding protein (Rhizobium sp. OAE497)
MTEALKIGILYSTTGPYGSMGRDARDGAEFALAEFAAARRIRIEPVFFDPHADLAAYLEG
ARQLLRAGCRHIVGTITSAARKEVIPLVEKHDGLLWYMCPYEGFEANENVIYVGGCPNQH
LIPLFEHLIPRFGARPYLVGANYVWGWEMNRLARELITNAGGEVLGERYLPLEEIAVERI
VADIEQRRPSFILNNLIGPSSYAFLAAIGKLAERDPAFRPENCPVVSCDLMECELADIEP
GRAIGQLCAASYFDNLSTPENLSFKIRVAARYGANRRVSSVFASAYTAVKLCADAIVEAG
TDEPAAVRRELYETQRPSLFGSIAIDRETNHAPLPFHLGQINTENGFDVVTSRPPLAADP
YLTGRNKPASPKLRVVS