Protein Info for ABIE40_RS19210 in Rhizobium sp. OAE497

Annotation: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 PF02527: GidB" amino acids 14 to 190 (177 residues), 118.2 bits, see alignment E=1.4e-38 TIGR00138: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG" amino acids 17 to 190 (174 residues), 114.4 bits, see alignment E=2.5e-37

Best Hits

Swiss-Prot: 71% identical to RSMG_RHIEC: Ribosomal RNA small subunit methyltransferase G (rsmG) from Rhizobium etli (strain CFN 42 / ATCC 51251)

KEGG orthology group: K03501, ribosomal RNA small subunit methyltransferase G [EC: 2.1.1.170] (inferred from 70% identity to rlg:Rleg_4255)

Predicted SEED Role

"rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.170

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (205 amino acids)

>ABIE40_RS19210 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG (Rhizobium sp. OAE497)
MKLNGQSVSRETQARLEHFLQLFQKWAKTINLVAPSTLSDAWDRHIVDSAQIYQLSPGAK
TWVDLGSGGGFPGVITAILMAEQANGWVHLVESNNKKASFLRLALRETNARGSVHAVRIE
DVYKEVPDSDAISGRALADLDKLLEFSKPWMDRNEECQAFFHKGRDYRSEIKKAHGRWQF
DLVEHTSVVERDSVILEISKLRHLV