Protein Info for ABIE40_RS19055 in Rhizobium sp. OAE497

Annotation: phosphatase PAP2 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 transmembrane" amino acids 31 to 49 (19 residues), see Phobius details amino acids 76 to 94 (19 residues), see Phobius details amino acids 114 to 134 (21 residues), see Phobius details amino acids 163 to 182 (20 residues), see Phobius details amino acids 187 to 207 (21 residues), see Phobius details amino acids 213 to 238 (26 residues), see Phobius details PF01569: PAP2" amino acids 115 to 228 (114 residues), 83.2 bits, see alignment E=7e-28

Best Hits

Swiss-Prot: 41% identical to LPXE_RHIEC: Lipid A 1-phosphatase (lpxE) from Rhizobium etli (strain CFN 42 / ATCC 51251)

KEGG orthology group: None (inferred from 41% identity to ret:RHE_CH04094)

Predicted SEED Role

"Phosphatidylglycerophosphatase B (EC 3.1.3.27)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 3.1.3.27)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.27

Use Curated BLAST to search for 3.1.3.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (252 amino acids)

>ABIE40_RS19055 phosphatase PAP2 family protein (Rhizobium sp. OAE497)
MSDTAGAKPGCKAYMKKRYEARRTIHRRVPWKAFALFAINAVAIAFFVFDRPLGQAVKSL
SPPLVSIAGDVTDIGRLAWILAGLATILLTGYVVRRRLWKVRRRFRMTYFGQMAAYVGLS
VVLASAIANPLKFLIGRARPLLYEQEGIFSFTPFSWDFLHQSFPSGHSANIGALFMSLAL
LFPRFRLVFIGIGLWLGATRVIIGVHYPSDVAAGLALGAWLAFALSIAFARFGFVFSVGR
EGWPIPRLSRLL