Protein Info for ABIE40_RS18585 in Rhizobium sp. OAE497

Annotation: aldose epimerase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 PF01263: Aldose_epim" amino acids 22 to 335 (314 residues), 268.4 bits, see alignment E=4.4e-84

Best Hits

KEGG orthology group: K01785, aldose 1-epimerase [EC: 5.1.3.3] (inferred from 87% identity to ara:Arad_4648)

Predicted SEED Role

"Aldose 1-epimerase (EC 5.1.3.3)" in subsystem Lactose and Galactose Uptake and Utilization or Maltose and Maltodextrin Utilization (EC 5.1.3.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.3.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (340 amino acids)

>ABIE40_RS18585 aldose epimerase family protein (Rhizobium sp. OAE497)
MAEQLKREVFGTTKNGETVYRVEIKGGGLTAKIMTWGAVIQDLRLDGHEAPLLLGFDNFA
DYPAYSSYFGATPGRCANRIGGGKFTLDGKAYQLELNEKGISHLHGGSDNIAKRNWTIVE
HDVDRVVLKIVDPDGRAGYPGNCTIQATYRVHGNGEFSIVYESTSDQPTLANVCQHAYFN
LDGRDDALGHDIMIAADHYLPTDERQIPTGELRPVDGTTFDFREMTSMKRFEGSEQALYD
HNFCLSKDRVAKRSVVLARSVNSGVSLEVRTTEPGVQFYAGFKLNVAVPGLDGRKYGPFA
GFCLETQVWPDAINHEGFPNAVLRPGEVLRQETDYIFSKS