Protein Info for ABIE40_RS17395 in Rhizobium sp. OAE497

Annotation: preprotein translocase subunit SecA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 904 PF07517: SecA_DEAD" amino acids 9 to 390 (382 residues), 435.2 bits, see alignment E=3.3e-134 TIGR00963: preprotein translocase, SecA subunit" amino acids 30 to 812 (783 residues), 1101.4 bits, see alignment E=0 PF00270: DEAD" amino acids 101 to 220 (120 residues), 30.4 bits, see alignment E=9.2e-11 PF01043: SecA_PP_bind" amino acids 234 to 347 (114 residues), 134.6 bits, see alignment E=6.7e-43 PF21090: P-loop_SecA" amino acids 406 to 611 (206 residues), 304.9 bits, see alignment E=8e-95 PF07516: SecA_SW" amino acids 613 to 825 (213 residues), 232.1 bits, see alignment E=1.9e-72 PF02810: SEC-C" amino acids 882 to 899 (18 residues), 41 bits, see alignment (E = 4e-14)

Best Hits

Swiss-Prot: 84% identical to SECA_AGRRK: Protein translocase subunit SecA (secA) from Agrobacterium radiobacter (strain K84 / ATCC BAA-868)

KEGG orthology group: K03070, preprotein translocase subunit SecA (inferred from 84% identity to ara:Arad_4157)

Predicted SEED Role

"Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (904 amino acids)

>ABIE40_RS17395 preprotein translocase subunit SecA (Rhizobium sp. OAE497)
MVSFGGIARKIFGSANDRRVRSFQPKVAAISAIEEKTKALSDEQLAAQTVEFRKQLADGK
TLDDILIPAFAVVREASRRVLGMRPFDVQLVGGMILHSGDIAEMKTGEGKTLVATLPVYL
NALSGKGVHVVTVNDYLAQRDAATMGKVYGFLGLTTGVIVHGLSDEERAAAYNCDITYAT
NNELGFDYLRDNMKYEKAQMVQRGHNFAIVDEVDSILVDEARTPLIISGPLDDRSDLYNT
IDAFIPLLSDGDYEIDEKQRSANFSEEGTEKLEGLLKQAGLLKGASLYDIENVAIVHHVN
NALKAHKLFQRDKDYIVRNDEIVIIDEFTGRMMPGRRYSEGQHQALEAKEKVKIQPENQT
LAQITFQNYFRMYGKLAGMTGTAQTEAEEFGNIYGLEVVEVPTNLPIQRIDEDDEVYRTF
EEKYKAIIAEIADAQKRGQPVLVGTTSIEKSELLADLMRKQGFKDFQVLNARYHEQEAYI
VAQAGVPGAVTIATNMAGRGTDIQLGGNLEMRVERELEGVEHGPEYDAKVEAIRAEIKQL
KEKALAAGGLYVIATERHESRRIDNQLRGRSGRQGDPGRSKFYLSLQDDLMRIFGSDRMD
GMLTKLGLKEGEAIVHPWINKALERAQKKVEARNFDIRKNLLKYDDVLNDQRKVIFDQRL
ELMEAANIAETVSDMRREVIEDLVDKHIPERAYAEQWDAAGLKEQVANLLNLDLPIEDWA
KEEGIGEDDIRERITEAANAAFTEKAERFGDDIMRYVERSILMQTLDHLWREHIVNLDHL
RSVIGFRGYAQRDPLQEYKSEAFELFQSLLNNLRQAVTAQLMRVELVQQAPAEPELPVMQ
AQHLDPDTGENDFAPIYQASEVIVAPENRDPNDPSTWGKVGRNEPCPCGSGKKFKHCHGA
FAEA