Protein Info for ABIE40_RS14650 in Rhizobium sp. OAE497

Annotation: urea ABC transporter ATP-binding protein UrtD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 TIGR03411: urea ABC transporter, ATP-binding protein UrtD" amino acids 10 to 251 (242 residues), 387.3 bits, see alignment E=1.5e-120 PF00005: ABC_tran" amino acids 26 to 181 (156 residues), 109.8 bits, see alignment E=1.8e-35

Best Hits

Swiss-Prot: 32% identical to LIVG_ECO57: High-affinity branched-chain amino acid transport ATP-binding protein LivG (livG) from Escherichia coli O157:H7

KEGG orthology group: K01995, branched-chain amino acid transport system ATP-binding protein (inferred from 96% identity to rlg:Rleg_3315)

MetaCyc: 32% identical to branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG (Escherichia coli K-12 substr. MG1655)
ABC-15-RXN [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]

Predicted SEED Role

"Urea ABC transporter, ATPase protein UrtD" in subsystem Urea decomposition

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (251 amino acids)

>ABIE40_RS14650 urea ABC transporter ATP-binding protein UrtD (Rhizobium sp. OAE497)
MIPDVKPNSVLYLDGVSVSFDGFKALNSLSIVIEPGELRAIIGPNGAGKTTMMDIITGKT
RPDEGAVFFNGQTDLTKLDEADIAQLGIGRKFQKPTVFESHTVWDNLELALNRRRGVFST
LFYRLSGDDKARIEEILETVRLTHRRDELAANLSHGQKQWLEIGMLLAQEPKLLLVDEPV
AGMTDAETAETAILLKEIAKTRSVVVVEHDMGFIRDLGVKVTCLAEGSVLAEGSIDFVSS
DPKVIENYLGR