Protein Info for ABIE40_RS14295 in Rhizobium sp. OAE497

Annotation: non-ribosomal peptide synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 638 PF00501: AMP-binding" amino acids 28 to 377 (350 residues), 299 bits, see alignment E=6.9e-93 TIGR01733: amino acid adenylation domain" amino acids 49 to 451 (403 residues), 396.1 bits, see alignment E=8.6e-123 PF13193: AMP-binding_C" amino acids 435 to 514 (80 residues), 34.7 bits, see alignment E=4.3e-12 PF00550: PP-binding" amino acids 544 to 606 (63 residues), 61 bits, see alignment E=1.7e-20

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (638 amino acids)

>ABIE40_RS14295 non-ribosomal peptide synthetase (Rhizobium sp. OAE497)
MTGLAYPGTIERSDTVSYDRDKGLPEIFRAHVQKNPSATALVFGSVSLTYRELDELSDKV
AVTLEERGVSRGDVVGLLLPRSLETIVCMLAALKAGAAYLPLDPAYPAEHLDYVIRECAP
KVIFAEAASIQKLALIPGLPSKVFDARAVIAEASASPTVRPAARPAGDDVAYVMFTSGST
GRPKGVVVAHRGIANLVLEQDFNPLTSKDVVLHAMTISFDASTLEIWSALLNGCKLVGMP
DLNFSISRLCDLIEEHGVTFHASTPGLFNLLADFGRDRVPSLRHVLFGGDVASVAHSLRF
LQSHPNCRLTNAYGPTEATVLVTGYNIPADFKGTEMPIGKAIGNTQILILDDHLHEVPVG
EEGQIALAGEGLGLGYFNRPELTRERFVMVETRDGPVRCYLTGDLGTMDADGTVHFHGRR
DRQVKINGKRIELDEIETALRNDTRLSEAAVVCQVMGPELKQMVAFLCPREDLRGRDQEL
TRDVMATLRGRLPAFMIPNSAIVIDQMPMTRAGKIDRSKLLAPVVEAAPSAIEIAADTGS
EAMLTRLWRDALGNKPVDLDTNFFDLGGTSLQLMQIHARMEAELGRQVPVVQLFKHSTIR
ELSRFLEGKHDNSGRDAAAALRAEQQRNNMARFRRNTK