Protein Info for ABIE40_RS14260 in Rhizobium sp. OAE497

Annotation: GMC family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 565 PF01266: DAO" amino acids 18 to 252 (235 residues), 33.8 bits, see alignment E=7e-12 PF05199: GMC_oxred_C" amino acids 414 to 539 (126 residues), 86.1 bits, see alignment E=8.9e-28

Best Hits

Predicted SEED Role

"Glucose-methanol-choline (GMC) oxidoreductase:NAD binding site" in subsystem Respiratory dehydrogenases 1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (565 amino acids)

>ABIE40_RS14260 GMC family oxidoreductase (Rhizobium sp. OAE497)
MSILDLRSMPVHTLLQADVAIIGAGPAGLTIARELSRKADVLVLDSGGLSYEPGPQVLNA
VENTGEPSGERRAPEGRGYNGSLSWLNDIPAFELRNRMLGGSTHTWVGKCAAFDEMDFAL
RPWLRLSGWPFERSELLPHLDRAAELLNLGPNVYDAGLHALLRTVPEKLNFDDRTLRYFF
WQFSHERQKRGEPMRFANVARSLALSGTKFLTNANVTEIRAEQRGHHSLSVASPEGNMAT
VRTKMVVLCCGGVENARLLLASNSMSSAGLGNARGTVGRYLADHPRTTLMRFRKSSDIDA
VARHFNFYGLKHDGAPHFYLRGLSLSPMIQAREGLTNCAAYPVQIHAADDPWAALKRLAK
GGGKRAISDLMTVLGSPGMLTSGAYQRLVKLRGLPHRSAELRFDVMAEQQLDPESRVTLS
EKLDRFGKPIARVNWKIGETEIESIARLAQTMSAEFRRLGLPEPELADWIAAGDPSAAAF
MDMAHPSCTTRMGSDAATSVVDGNSMVHGVEGVYVAGSSVFPTAGHANPTLMLVALSMRL
ADHLQERLAEERRPLPGSQPSRQVS