Protein Info for ABIE40_RS13390 in Rhizobium sp. OAE497

Annotation: xanthine dehydrogenase family protein molybdopterin-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 719 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF20256: MoCoBD_2" amino acids 50 to 192 (143 residues), 45.1 bits, see alignment E=9.6e-16 amino acids 588 to 668 (81 residues), 53.2 bits, see alignment E=3.3e-18 PF02738: MoCoBD_1" amino acids 317 to 545 (229 residues), 116.7 bits, see alignment E=9.5e-38

Best Hits

KEGG orthology group: K07303, isoquinoline 1-oxidoreductase, beta subunit [EC: 1.3.99.16] (inferred from 56% identity to rsk:RSKD131_3338)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (719 amino acids)

>ABIE40_RS13390 xanthine dehydrogenase family protein molybdopterin-binding subunit (Rhizobium sp. OAE497)
MTIQEIATTRRGFLAGTGGLVIGFALMPKSSAFAAEKGVQAGGADALVTLNTFVRIGSDD
TVTILSKHIEFGQGPFTGLATLVAEELDADWGQMRAVHSPADDKVYANLAFGLQGTGGSS
SIANSYEQFRQAGATARAMLVAAAADEWNVPAGEITVEKGRVRHAASGKDSGFGALATKA
AGIKPPADVKLKDPSKFTLIGQELPKLDTVSKTNGQAVYTLDIVPDNLLVAVVAHPNHFG
AGVKSFDDSETRKVKGVVDVKQLPQGVAVYADNTFAALKGRSVLKVDWDLSKAETRSSDQ
LSADYAKALGEKGITASEKGDVEKAFTDTGLKTLEAQIIFPFLAHAPMEPLDAVFIKASD
GSLDVYNGAQFPGMDKATAAKITGIDPAKVRLNTQITGGSFGRKAQFGSPYMQEAASVFA
ATDQSRPVKHMWTREDDIRGGYYRPMYLHKMRGAINADGRIVAWDQAIVGQSIMGKADLD
STSVEGASDLPYDVPNLRVVSHNVKLAIPPLWWRSVGHTHTGFAVETFLDELFQMVGKDP
VEGRLEQLTEDPRYAGVLKKAAELADWGGTVQEGRQRGVAVVKSFNTYVGQVVEVSAGAD
GAPRVHKVWCAVDCGVAINPNVIKAQMEGGIGYGLGAVLFDAVTLGEGGAIMQSNFHDYR
SIRINEMPDVEVAVIKSGEPPTGVGEPGVPPVGPATANAWRRLTGAPVRSLPIVAVATS