Protein Info for ABIE40_RS12250 in Rhizobium sp. OAE497

Annotation: response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 211 PF00072: Response_reg" amino acids 8 to 116 (109 residues), 101.9 bits, see alignment E=2.4e-33 PF00196: GerE" amino acids 142 to 197 (56 residues), 62 bits, see alignment E=3.1e-21

Best Hits

Swiss-Prot: 53% identical to NODW_BRADU: Nodulation protein W (nodW) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: None (inferred from 59% identity to rhi:NGR_b16840)

Predicted SEED Role

"Nitrogen regulation protein NR(I)" in subsystem Ammonia assimilation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (211 amino acids)

>ABIE40_RS12250 response regulator (Rhizobium sp. OAE497)
MHGKDHIVFVVDDDKRVREGLSEFLEASQLNVVTFATGREYLDAPKPDTPSCLILDVRLP
DVNGMEIQAKLSDNAHPPIIFITGHGDIQMTVRAMKLGAVDFLTKPFREDALLTAIVTAL
ERDKIARQERAELLDLQAKLDCLSARERDVLPLVVSGLMNKQGAAKLGISEITFQIHRGN
MMRKMHADSLADLVRIAGKLNIPITHTRYGN