Protein Info for ABIE40_RS11550 in Rhizobium sp. OAE497

Annotation: class I SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 409 PF08421: Methyltransf_13" amino acids 5 to 66 (62 residues), 76.2 bits, see alignment E=4.7e-25 PF13489: Methyltransf_23" amino acids 93 to 239 (147 residues), 55.7 bits, see alignment E=1.3e-18 PF08241: Methyltransf_11" amino acids 105 to 196 (92 residues), 30.1 bits, see alignment E=1.6e-10 PF08242: Methyltransf_12" amino acids 105 to 195 (91 residues), 33 bits, see alignment E=2.1e-11 PF08484: Methyltransf_14" amino acids 247 to 404 (158 residues), 200.6 bits, see alignment E=3.5e-63

Best Hits

KEGG orthology group: None (inferred from 74% identity to rhi:NGR_c24360)

MetaCyc: 38% identical to D-olivose 4-ketoreductase (Streptomyces argillaceus)
2.1.1.-; 1.1.1.-

Predicted SEED Role

"FIG01163484: hypothetical protein"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (409 amino acids)

>ABIE40_RS11550 class I SAM-dependent methyltransferase (Rhizobium sp. OAE497)
MVHACRFCSTPLTNVVADLGATPWSNSFLPNEAAIETERSFPLKVMVCSECFLVQTTETV
PPGEIFNAEYAYFSSFSTSWLDHAKRYTQLMTERFGLGDQSTVIEVASNDGYLLQYFAAA
GVKVLGVEPAANAAEVAEGRGVPTKVAFFGSDTAKAIVESGIRADLTAANNVLAHVPDIA
DFVRGFQIVLKPEGVATFEFPHLLRMIEGLQFDTIYHEHYSYISLLAAERIFEACGLKVF
DVEELSTHGGSLRVYAQRNDGVRVPTERLLAMREEEERFGLKDMRTYREFGTRIAAVCDA
FRDFLRQARDEGKVVAAYGAAAKGNTFLNVCGVTRDDISFVVDRSTVKQGKLLPGSHIPV
YAPSELERAKPDYVVILPWNLTAEIVESCKYIADWGGRFVTAIPTLRIL