Protein Info for ABIE40_RS09895 in Rhizobium sp. OAE497

Annotation: acyl-CoA carboxylase subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01039: Carboxyl_trans
  • amino acids 27 to 508 (482 residues), 648.4 bits, E=3.7e-199

Best Hits

Swiss-Prot: 76% identical to PCCB_RHOS4: Propionyl-CoA carboxylase beta chain (pccB) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)

KEGG orthology group: K01966, propionyl-CoA carboxylase beta chain [EC: 6.4.1.3] (inferred from 94% identity to rle:RL2563)

MetaCyc: 76% identical to propionyl-CoA carboxylase beta subunit (Cereibacter sphaeroides)
Propionyl-CoA carboxylase. [EC: 6.4.1.3]

Predicted SEED Role

"Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)" in subsystem Serine-glyoxylate cycle (EC 6.4.1.3)

MetaCyc Pathways

• propanoyl CoA degradation I (3/3 steps found)
• 2-oxobutanoate degradation I (3/4 steps found)
• anaerobic energy metabolism (invertebrates, mitochondrial) (7/10 steps found)
• superpathway of anaerobic energy metabolism (invertebrates) (12/17 steps found)
• 3-hydroxypropanoate cycle (7/13 steps found)
• superpathway of L-methionine salvage and degradation (9/16 steps found)
• methylaspartate cycle (11/19 steps found)
• 3-hydroxypropanoate/4-hydroxybutanate cycle (10/18 steps found)
• superpathway of the 3-hydroxypropanoate cycle (7/18 steps found)
• mycolate biosynthesis (26/205 steps found)
• superpathway of mycolate biosynthesis (27/239 steps found)

KEGG Metabolic Maps

• Propanoate metabolism
• Valine, leucine and isoleucine degradation

Isozymes

Compare fitness of predicted isozymes for: 6.4.1.3

Use Curated BLAST to search for 6.4.1.3

Protein Sequence (510 amino acids)

>ABIE40_RS09895 acyl-CoA carboxylase subunit beta (Rhizobium sp. OAE497)
MKEILEELERRRDAARLGGGEARIEAQHKRGKLTARERIDLILDEDSFEEFDMFVEHRST
DFGMEKSRIAGDGVVTGWGTVNGRTVFVFAKDFTVFGGSLSEAHAEKIMKVQDMALKNRA
PIIGIYDAGGARIQEGVAALGGYAEVFQRNVLASGVIPQISVIMGPCAGGDVYSPAMTDF
IFMVRDTSYMFVTGPDVVKTVTNETVTAEELGGASVHTTRSSIADGAYDNDVDTLLQVRR
LIDFLPQSNTSPIPEIECYQPVTESDESLDTLVPANANKPYDIKELILKVADEGDFFEIQ
ASFGKNIVCGFGRIEGSTVGFVANQPMVLAGVLDSDASRKAARFVRFCDCFNIPLVTFVD
VPGFLPGTAQEYGGLIKHGAKLLFAYAEATVPKLTVITRKAFGGAYDVMASKHLRGDLNY
AWPTAQIAVMGAKGAVEIIFRKDIADPEKIAAHTKMYEDRFLSPFVAAERGYIDEVIMPH
STRRRLARGLKMLRNKDLSNPWKKHDNIPL