Protein Info for ABIE40_RS08215 in Rhizobium sp. OAE497

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 32 to 55 (24 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details amino acids 133 to 154 (22 residues), see Phobius details amino acids 166 to 191 (26 residues), see Phobius details amino acids 205 to 224 (20 residues), see Phobius details PF20973: VUPS" amino acids 17 to 220 (204 residues), 272.8 bits, see alignment E=1.7e-85 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 255 to 413 (159 residues), 148.8 bits, see alignment E=6.1e-48 PF00990: GGDEF" amino acids 258 to 410 (153 residues), 130 bits, see alignment E=7.3e-42

Best Hits

KEGG orthology group: None (inferred from 79% identity to rlt:Rleg2_1423)

Predicted SEED Role

"Serine phosphatase RsbU, regulator of sigma subunit" in subsystem SigmaB stress responce regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (422 amino acids)

>ABIE40_RS08215 GGDEF domain-containing protein (Rhizobium sp. OAE497)
MEATNLGLFVLEAIGYFGLMVTLLHFRNRLGLGVFVTALGVMHFMETYLAAVFYVNLPFG
VASPGSSVFFAGKLMMILMLYLQEDASTVRQPIYGLFIGNLLTVAIAWILQLHHTIEMSP
GNEADFGFLKEMGWLMIWGTAILYLDSIGIILLYERLGRYIKRKVILRFMICGFVLLTFD
QVGFFGGLHYFLGVPLSAFWDGWKAKMFAVCVYTVLFALYEIYVRRDGVPAAARSISDVF
GDLTFRERYNDLLDRTGRDILTGVYDRSRMELEAPVMIREAQRQGLYGTVIIIDADHFKD
MNDNFGHLQGDEVLKAIAGRLGTILRSADRVFRFGGEEFVAVCPGTDHEEGLIVAERLRW
TIATSVKTPDGKPVTVSIGVATADEDGVSFTTVLAAADDRLYQAKKSGRNCVVGRSGLVK
VG