Protein Info for ABIE40_RS07370 in Rhizobium sp. OAE497

Annotation: glycerol-3-phosphate 1-O-acyltransferase PlsY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase
  • amino acids 14 to 204 (191 residues), 176.3 bits, E=3.1e-56
• PF02660: G3P_acyltransf
  • amino acids 21 to 194 (174 residues), 182.7 bits, E=2.9e-58

Best Hits

Swiss-Prot: 79% identical to PLSY1_RHIL3: Glycerol-3-phosphate acyltransferase 1 (plsY1) from Rhizobium leguminosarum bv. viciae (strain 3841)

KEGG orthology group: K08591, glycerol-3-phosphate acyltransferase PlsY [EC: 2.3.1.15] (inferred from 79% identity to rlg:Rleg_1389)

Predicted SEED Role

"Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria

MetaCyc Pathways

• phosphatidylglycerol biosynthesis I (6/6 steps found)
• phosphatidylglycerol biosynthesis II (6/6 steps found)
• CDP-diacylglycerol biosynthesis I (4/4 steps found)
• CDP-diacylglycerol biosynthesis II (4/4 steps found)
• superpathway of phospholipid biosynthesis III (E. coli) (9/12 steps found)
• oleate biosynthesis III (cyanobacteria) (2/3 steps found)
• phosphatidate biosynthesis (yeast) (3/5 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (8/13 steps found)
• diacylglycerol and triacylglycerol biosynthesis (3/7 steps found)
• palmitoyl ethanolamide biosynthesis (2/6 steps found)
• superpathway of stearidonate biosynthesis (cyanobacteria) (2/6 steps found)
• stigma estolide biosynthesis (2/7 steps found)
• anandamide biosynthesis II (2/8 steps found)
• anandamide biosynthesis I (3/12 steps found)
• superpathway of phospholipid biosynthesis II (plants) (12/28 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism
• Glycerophospholipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.15

Use Curated BLAST to search for 2.3.1.15

Protein Sequence (206 amino acids)

>ABIE40_RS07370 glycerol-3-phosphate 1-O-acyltransferase PlsY (Rhizobium sp. OAE497)
MISELTNWQIALPMALVAAVVGYLLGSIPFGLILTRAAGLGDVRNIGSGNIGATNVLRTG
NKKLAAATLLLDALKATVAAWIMAYVAGPEASAIAGLFAFLGHLFPVWLGFKGGKGVATY
IGTLLGIAPLFVLVFAAIWLAVAFIFRYSSLAALTAMLVIPVALWIFGAEKVAAVMAIMS
VISYYKHKANISRLISGTESKIGAKG