Protein Info for ABIE40_RS07240 in Rhizobium sp. OAE497

Annotation: NADH-quinone oxidoreductase subunit L

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 665 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 33 to 54 (22 residues), see Phobius details amino acids 85 to 105 (21 residues), see Phobius details amino acids 117 to 134 (18 residues), see Phobius details amino acids 140 to 159 (20 residues), see Phobius details amino acids 180 to 198 (19 residues), see Phobius details amino acids 233 to 255 (23 residues), see Phobius details amino acids 269 to 287 (19 residues), see Phobius details amino acids 299 to 320 (22 residues), see Phobius details amino acids 327 to 353 (27 residues), see Phobius details amino acids 357 to 376 (20 residues), see Phobius details amino acids 396 to 420 (25 residues), see Phobius details amino acids 440 to 465 (26 residues), see Phobius details amino acids 486 to 504 (19 residues), see Phobius details amino acids 537 to 559 (23 residues), see Phobius details amino acids 641 to 661 (21 residues), see Phobius details TIGR01974: proton-translocating NADH-quinone oxidoreductase, chain L" amino acids 3 to 660 (658 residues), 906.8 bits, see alignment E=5.1e-277 PF00662: Proton_antipo_N" amino acids 68 to 118 (51 residues), 82.1 bits, see alignment 3.2e-27 PF00361: Proton_antipo_M" amino acids 134 to 442 (309 residues), 287.6 bits, see alignment E=1.6e-89 PF06455: NADH5_C" amino acids 456 to 504 (49 residues), 28.5 bits, see alignment 1.7e-10

Best Hits

KEGG orthology group: K00341, NADH dehydrogenase I subunit L [EC: 1.6.5.3] (inferred from 92% identity to rec:RHECIAT_CH0001688)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (665 amino acids)

>ABIE40_RS07240 NADH-quinone oxidoreductase subunit L (Rhizobium sp. OAE497)
MFLYKAIVFLPLIGAIIAGLFGRAIGAKASEYVTSGLMIIAAALSWYVFFTVALGHPEGA
IKVEVLRWIQSGGIDVSWSLRIDTLTSVMLIVVNTVSTLVHIYSIGYMHHDPHRPRFFAY
LSLFTFAMLMLVTSDNLLQMFFGWEGVGLASYLLIGFWFKKPSASAAAMKAFIVNRVGDF
GFVLGIAGVFVLFGAINFDTIFANAANFAPHEGAEAASEVVLNLFGMQLDKTHALTAVCL
LLFMGAMGKSAQFLLHTWLPDAMEGPTPVSALIHAATMVTAGVFLVARMSPLFELSHDAL
TFVTIIGAITAFFAATVGLVQNDIKRVIAYSTCSQLGYMFVALGVGAYGAAIFHLFTHAF
FKALLFLCAGSVIHAVDGEQDMRYMGGLRPHIKVTFWMMMIGTLAITGVGIPFTPIGFAG
FFSKDVIIEATYASHSPAAGFAFTLLVIAALFTSFYSWRLIFLTFFGKPRASHEVMHHVH
ESPQVMLVPLYILAIGAVFAGFLFEGRFYGEEYAEFWKGALFTSKENELLEHFHHVPALV
ALSPFIAMVIGFVTAWYMYIKSPSTPRVLAQQHRVLYQFLLNKWYFDELYDFLFVRSAKA
LGNFLWKKGDVGVIDTYGPNGIAARVVDVTNRVVRLQTGYLYHYAFAMLIGIAALVTWMM
LGSSF