Protein Info for ABIE40_RS05005 in Rhizobium sp. OAE497

Annotation: Na+/H+ antiporter subunit D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 517 transmembrane" amino acids 22 to 43 (22 residues), see Phobius details amino acids 52 to 71 (20 residues), see Phobius details amino acids 90 to 119 (30 residues), see Phobius details amino acids 129 to 148 (20 residues), see Phobius details amino acids 154 to 172 (19 residues), see Phobius details amino acids 184 to 206 (23 residues), see Phobius details amino acids 226 to 251 (26 residues), see Phobius details amino acids 260 to 283 (24 residues), see Phobius details amino acids 294 to 314 (21 residues), see Phobius details amino acids 321 to 341 (21 residues), see Phobius details amino acids 348 to 369 (22 residues), see Phobius details amino acids 389 to 408 (20 residues), see Phobius details amino acids 426 to 452 (27 residues), see Phobius details amino acids 464 to 486 (23 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 149 to 440 (292 residues), 174.7 bits, see alignment E=1.3e-55

Best Hits

KEGG orthology group: K05568, multicomponent Na+:H+ antiporter subunit D (inferred from 74% identity to rlt:Rleg2_0877)

Predicted SEED Role

"Na(+) H(+) antiporter subunit D" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (517 amino acids)

>ABIE40_RS05005 Na+/H+ antiporter subunit D (Rhizobium sp. OAE497)
MAASTTPIADLSTAMLTAPVSAGHWLVILPVALCIVLGALLLTLRAHVRLHAPIAVSGLA
ALVVVDALLLQKVIAEGPVTMVMGRWLPPFGIAFTADLFGALMALAAAIAALAGSLYALA
DTDAGHRRFGFFPLLLLLMAGVSGAFLTGDVFNLYVWFEVLLISSFGLLILGSERRQIDG
AMKYAVLNLIATTLFLTAVGYLYAIFGTLNMADVAQKAAGLRDSAPLVTLAALFLFAFAI
KAAAFPVNFWLPASYHTPRIVVSALFAGLLTKVGIYALIRVMVMLMPVEREELSLLIAVL
GAATTLAGALGALAQTDIRRLLGYVVISGIGNMLVGISIGTPGGVSGAIFYALHSIVLMV
ALYFAAGIAGRLGGSFSLASLGGLYRARGWFAAVSLILFFAASGLPPFSGFWPKLMLVKA
SLDVGAWWLAASLLVGGFLTTICFGRVFLLAYWRPAGEAAAPAAIGWTMTVPLLLLTALV
VAFGILPEQLLSLTQSAAESLADPSAYIHSVFPGGVP